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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
8
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pubmed:dateCreated |
2004-4-9
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pubmed:abstractText |
FHIT and WWOX are a tumor suppressor and a candidate suppressor that encompass the FRA3B and FRA16D fragile sites at chromosomes 3p14.2 and 16q23.3-24.1, respectively. Reduced or absent Fhit expression has been reported in two-thirds of invasive breast tumors in association with adverse prognostic factors. Loss of 16q has been reported frequently in low-grade, invasive breast tumors.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
0008-543X
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pubmed:author |
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pubmed:copyrightInfo |
Copyright 2004 American Cancer Society.
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pubmed:issnType |
Print
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pubmed:day |
15
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pubmed:volume |
100
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1605-14
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:15073846-Acid Anhydride Hydrolases,
pubmed-meshheading:15073846-Adult,
pubmed-meshheading:15073846-Breast Neoplasms,
pubmed-meshheading:15073846-Carcinoma,
pubmed-meshheading:15073846-Carrier Proteins,
pubmed-meshheading:15073846-Cell Transformation, Neoplastic,
pubmed-meshheading:15073846-Chromosomes, Human, Pair 16,
pubmed-meshheading:15073846-Chromosomes, Human, Pair 3,
pubmed-meshheading:15073846-Female,
pubmed-meshheading:15073846-Gene Expression Profiling,
pubmed-meshheading:15073846-Gene Expression Regulation, Neoplastic,
pubmed-meshheading:15073846-Genes, Tumor Suppressor,
pubmed-meshheading:15073846-Humans,
pubmed-meshheading:15073846-Immunohistochemistry,
pubmed-meshheading:15073846-Middle Aged,
pubmed-meshheading:15073846-Neoplasm Invasiveness,
pubmed-meshheading:15073846-Neoplasm Proteins,
pubmed-meshheading:15073846-Prognosis,
pubmed-meshheading:15073846-Receptors, Estrogen
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pubmed:year |
2004
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pubmed:articleTitle |
The fragile genes FHIT and WWOX are inactivated coordinately in invasive breast carcinoma.
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pubmed:affiliation |
Department of Pathology, Hacettepe University, Ankara, Turkey. gulnurguler@yahoo.com
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
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