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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
7
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pubmed:dateCreated |
2004-4-9
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pubmed:abstractText |
WWOX (WW domain containing oxidoreductase) is a tumor suppressor gene that maps to the common fragile site FRA16D. We showed previously that WWOX is frequently altered in human lung and esophageal cancers. The purpose of this study was to delineate more precisely the role of WWOX in pancreatic carcinogenesis.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Antimetabolites, Antineoplastic,
http://linkedlifedata.com/resource/pubmed/chemical/Azacitidine,
http://linkedlifedata.com/resource/pubmed/chemical/DNA, Complementary,
http://linkedlifedata.com/resource/pubmed/chemical/Oxidoreductases,
http://linkedlifedata.com/resource/pubmed/chemical/RNA, Messenger,
http://linkedlifedata.com/resource/pubmed/chemical/Tumor Suppressor Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/WWOX protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/decitabine
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pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
1078-0432
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pubmed:author |
pubmed-author:AlderHansjuergH,
pubmed-author:AqeilanRami IRI,
pubmed-author:CesariRossanoR,
pubmed-author:CroceCarlo MCM,
pubmed-author:KanematsuTakashiT,
pubmed-author:KurokiTamotsuT,
pubmed-author:MatsuyamaAyumiA,
pubmed-author:MoriMasakiM,
pubmed-author:NolliMaria LML,
pubmed-author:RattanShashiS,
pubmed-author:TrapassoFrancescoF,
pubmed-author:WilliamsNoel NNN,
pubmed-author:YendamuriSaiS
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pubmed:issnType |
Print
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pubmed:day |
1
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pubmed:volume |
10
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
2459-65
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:15073125-Adenocarcinoma,
pubmed-meshheading:15073125-Alleles,
pubmed-meshheading:15073125-Antimetabolites, Antineoplastic,
pubmed-meshheading:15073125-Apoptosis,
pubmed-meshheading:15073125-Azacitidine,
pubmed-meshheading:15073125-Blotting, Western,
pubmed-meshheading:15073125-Cell Cycle,
pubmed-meshheading:15073125-Cell Line, Tumor,
pubmed-meshheading:15073125-Cell Separation,
pubmed-meshheading:15073125-Cell Transformation, Neoplastic,
pubmed-meshheading:15073125-DNA, Complementary,
pubmed-meshheading:15073125-DNA Methylation,
pubmed-meshheading:15073125-DNA Mutational Analysis,
pubmed-meshheading:15073125-Exons,
pubmed-meshheading:15073125-Flow Cytometry,
pubmed-meshheading:15073125-Genes, Tumor Suppressor,
pubmed-meshheading:15073125-Humans,
pubmed-meshheading:15073125-Loss of Heterozygosity,
pubmed-meshheading:15073125-Oxidoreductases,
pubmed-meshheading:15073125-Pancreatic Neoplasms,
pubmed-meshheading:15073125-Promoter Regions, Genetic,
pubmed-meshheading:15073125-Protein Structure, Tertiary,
pubmed-meshheading:15073125-RNA, Messenger,
pubmed-meshheading:15073125-Reverse Transcriptase Polymerase Chain Reaction,
pubmed-meshheading:15073125-Transfection,
pubmed-meshheading:15073125-Tumor Suppressor Proteins
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pubmed:year |
2004
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pubmed:articleTitle |
The tumor suppressor gene WWOX at FRA16D is involved in pancreatic carcinogenesis.
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pubmed:affiliation |
Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, Pennsylvania 19107, USA.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
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