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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
15
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pubmed:dateCreated |
2004-4-20
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pubmed:abstractText |
Platelet activation is a feature of many cardiovascular diseases characterized by endothelial dysfunction. The mechanistic relationship between impaired systemic nitric oxide (NO) bioavailability and platelet activation in vivo remains unclear. We investigated whether acute inhibition of NO production in humans modulates platelet activation in vivo and whether exogenous NO would counteract such an effect.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Antigens, CD,
http://linkedlifedata.com/resource/pubmed/chemical/Antigens, CD63,
http://linkedlifedata.com/resource/pubmed/chemical/CD40 Ligand,
http://linkedlifedata.com/resource/pubmed/chemical/CD63 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Cell Adhesion Molecules,
http://linkedlifedata.com/resource/pubmed/chemical/Enzyme Inhibitors,
http://linkedlifedata.com/resource/pubmed/chemical/Fibrinogen,
http://linkedlifedata.com/resource/pubmed/chemical/Microfilament Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Nitric Oxide,
http://linkedlifedata.com/resource/pubmed/chemical/Nitric Oxide Donors,
http://linkedlifedata.com/resource/pubmed/chemical/Nitric Oxide Synthase,
http://linkedlifedata.com/resource/pubmed/chemical/Nitroglycerin,
http://linkedlifedata.com/resource/pubmed/chemical/P-Selectin,
http://linkedlifedata.com/resource/pubmed/chemical/Phosphoproteins,
http://linkedlifedata.com/resource/pubmed/chemical/Platelet Membrane Glycoproteins,
http://linkedlifedata.com/resource/pubmed/chemical/omega-N-Methylarginine,
http://linkedlifedata.com/resource/pubmed/chemical/vasodilator-stimulated...
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pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
1524-4539
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:day |
20
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pubmed:volume |
109
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1819-22
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:15066953-Adult,
pubmed-meshheading:15066953-Antigens, CD,
pubmed-meshheading:15066953-Antigens, CD63,
pubmed-meshheading:15066953-CD40 Ligand,
pubmed-meshheading:15066953-Cell Adhesion Molecules,
pubmed-meshheading:15066953-Enzyme Inhibitors,
pubmed-meshheading:15066953-Fibrinogen,
pubmed-meshheading:15066953-Humans,
pubmed-meshheading:15066953-Kinetics,
pubmed-meshheading:15066953-Male,
pubmed-meshheading:15066953-Microfilament Proteins,
pubmed-meshheading:15066953-Nitric Oxide,
pubmed-meshheading:15066953-Nitric Oxide Donors,
pubmed-meshheading:15066953-Nitric Oxide Synthase,
pubmed-meshheading:15066953-Nitroglycerin,
pubmed-meshheading:15066953-P-Selectin,
pubmed-meshheading:15066953-Phosphoproteins,
pubmed-meshheading:15066953-Platelet Activation,
pubmed-meshheading:15066953-Platelet Membrane Glycoproteins,
pubmed-meshheading:15066953-omega-N-Methylarginine
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pubmed:year |
2004
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pubmed:articleTitle |
Rapid regulation of platelet activation in vivo by nitric oxide.
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pubmed:affiliation |
Department of Cardiovascular Medicine, University of Oxford, UK.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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