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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
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pubmed:dateCreated |
1992-9-22
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pubmed:abstractText |
We have determined the chromosomal location of seven human neuronal nicotinic acetylcholine receptor subunit genes by genomic Southern analysis of hamster/human somatic cell hybrid DNAs. The beta 2 subunit gene was localized to human chromosome 1, the alpha 2 and beta 3 subunit genes were localized to human chromosome 8, the alpha 3, alpha 5, and beta 4 subunit genes were localized to human chromosome 15, and the alpha 4 subunit gene was localized to human chromosome 20. Mapping of the beta 2 subunit gene to chromosome 1 establishes a syntenic group with the amylase gene locus on human chromosome 1 and mouse chromosome 3, while mapping of the alpha 3 subunit gene to chromosome 15 confirms the existence of a syntenic group with the mannose phosphate isomerase gene locus on human chromosome 15 and mouse chromosome 9.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Aug
|
pubmed:issn |
0888-7543
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
13
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
962-7
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:1505988-Animals,
pubmed-meshheading:1505988-Blotting, Southern,
pubmed-meshheading:1505988-Chromosome Mapping,
pubmed-meshheading:1505988-Chromosomes, Human, Pair 1,
pubmed-meshheading:1505988-Chromosomes, Human, Pair 15,
pubmed-meshheading:1505988-Chromosomes, Human, Pair 8,
pubmed-meshheading:1505988-Cricetinae,
pubmed-meshheading:1505988-DNA,
pubmed-meshheading:1505988-DNA Probes,
pubmed-meshheading:1505988-Humans,
pubmed-meshheading:1505988-Hybrid Cells,
pubmed-meshheading:1505988-Neurons,
pubmed-meshheading:1505988-Receptors, Nicotinic
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pubmed:year |
1992
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pubmed:articleTitle |
Chromosomal localization of seven neuronal nicotinic acetylcholine receptor subunit genes in humans.
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pubmed:affiliation |
David Mahoney Institute of Neurological Sciences, University of Pennsylvania, Philadelphia 19104-6074.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
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