Linked Life Data

15058252

Source:http://linkedlifedata.com/resource/pubmed/id/15058252

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
90
pubmed:dateCreated
2004-4-2
pubmed:abstractText
In fifty two postmenopausal women (study group: n = 20 with varicose vein; controls: n = 32) with climacteric symptoms some changes in fibrinolytic and coagulative parameters were measured during six months of HRT consisted of transdermal oestradiol (17 beta-E2) and oral medroxyprogesterone acetate (MPA). Additionally, sonographic examinations of the venous system of pelvis minor and low extremities were performed three times in every women--at baseline, in the 3rd and the 6th month of the trial. In the 3rd month the varicose vein group exhibited lowered INR and t-PA, but the in 6th month increased D-dimer as compared to the controls. No sonographic signs of venous thromboembolism were detected. CONCLUSIONS: 1) Postmenopausal varicose vein women taking combined HRT (17 beta-E2 plus MPA) are on slightly increased additional risk of venous thromboembolism, 2) in monitoring of these patients sonographic evaluation of the venous system of low extremities and pelvis minor and well as D-dimer in blood serum should be done.
pubmed:language
pol
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
1426-9686
pubmed:author
pubmed:issnType
Print
pubmed:volume
15
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
521-4
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
2003
pubmed:articleTitle
[The impact of hormone replacement therapy applied in women with varicose vein on changes in coagulation and fibrinolysis].
pubmed:affiliation
Klinika Ginekologii i Chorób Menopauzy Instytutu Centrum Zdrowia Matki Polki w ?odzi.
pubmed:publicationType
Journal Article, Clinical Trial, English Abstract