Linked Life Data

15058159

Source:http://linkedlifedata.com/resource/pubmed/id/15058159

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
11-12
pubmed:dateCreated
2004-4-2
pubmed:abstractText
The aim of this study was to examine the levels of some soluble receptors of cytokines in sera from patients with systemic sclerosis (SSc) and to evaluate their role as parameters of disease activity and severity. Fifty-four patients with SSc were included in the study. Concentrations of the soluble receptors: sIL-2R, sTNF alpha RI and sIL-6R were determined by an enzyme-linked immunosorbent assay-ELISA. Controls were healthy age- and sex-matched volunteers. The study demonstrated that soluble receptors levels: sII-2R, sIL-6R and sTNF alpha RI were elevated in SSc patients and correlated with progress and severity of the disease. The most important correlations were found for sIL-2R levels, which were increased in 66.7% of patients. The raised levels of sTNF alpha RI were found in 32.4% of patients, and sIL-6R in 23.7% of patients. The concentrations were elevated in diffuse form of SSc and in patients with rapid systemic progression.
pubmed:language
pol
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0043-5147
pubmed:author
pubmed:issnType
Print
pubmed:volume
56
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
532-6
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
2003
pubmed:articleTitle
[Soluble receptors of cytokines in sera of patients with systemic sclerosis--clinical correlation].
pubmed:affiliation
Katedry i Kliniki Dermatologii Slaskiej Akademii Medycznej w Katowicach.
pubmed:publicationType
Journal Article, English Abstract