Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
7
pubmed:dateCreated
2004-6-28
pubmed:abstractText
Delayed liver single-photon emission computed tomography (SPECT) after (99m)Tc red blood cell (RBC) labelling is helpful in detecting hepatic haemangiomas; however, diagnosis can be difficult when lesions are situated adjacent to structures like the inferior vena cava, the heart or hepatic vessels, where blood activity persists. The aims of this study were to evaluate the usefulness of RBC SPECT and transmission computed tomography (RBC SPECT/CT) performed simultaneously with a hybrid imaging system for correct characterisation of hepatic lesions in patients with suspected haemangioma, and to assess the additional value of fused images compared with SPECT alone. Twelve patients with 24 liver lesions were studied. The acquisitions of both anatomical (CT) and functional (SPECT) data were performed during a single session. SPECT images were first interpreted alone and then re-evaluated after adding the transmission anatomical maps. Image fusion was successful in all patients, with perfect correspondence between SPECT and CT data, allowing the precise anatomical localisation of sites of increased blood pool activity. SPECT/CT had a significant impact on results in four patients (33.3%) with four lesions defined as indeterminate on SPECT images, accurately characterising the hot spot foci located near vascular structures. In conclusion, RBC SPECT/CT imaging using this hybrid SPECT/CT system is feasible and useful in the identification or exclusion of suspected hepatic haemangiomas located near regions with high vascular activity.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
1619-7070
pubmed:author
pubmed:issnType
Print
pubmed:volume
31
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1011-5
pubmed:meshHeading
pubmed-meshheading:15057491-Adult, pubmed-meshheading:15057491-Aged, pubmed-meshheading:15057491-Aged, 80 and over, pubmed-meshheading:15057491-Equipment Failure Analysis, pubmed-meshheading:15057491-Erythrocytes, pubmed-meshheading:15057491-Female, pubmed-meshheading:15057491-Hemangioma, pubmed-meshheading:15057491-Humans, pubmed-meshheading:15057491-Liver Neoplasms, pubmed-meshheading:15057491-Male, pubmed-meshheading:15057491-Middle Aged, pubmed-meshheading:15057491-Radiopharmaceuticals, pubmed-meshheading:15057491-Reproducibility of Results, pubmed-meshheading:15057491-Sensitivity and Specificity, pubmed-meshheading:15057491-Subtraction Technique, pubmed-meshheading:15057491-Technetium, pubmed-meshheading:15057491-Tomography, Emission-Computed, Single-Photon, pubmed-meshheading:15057491-Tomography, X-Ray Computed
pubmed:year
2004
pubmed:articleTitle
Technetium-99m-labelled red blood cell imaging in the diagnosis of hepatic haemangiomas: the role of SPECT/CT with a hybrid camera.
pubmed:affiliation
Department of Biopathology and Diagnostic Imaging, University Tor Vergata, Rome, Italy. oschil@tiscalinet.it
pubmed:publicationType
Journal Article, Clinical Trial