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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
8
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pubmed:dateCreated |
1992-9-23
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pubmed:abstractText |
Surfactant-associated protein (SP-A) was measured in tracheal aspirates of ventilated infants with (n = 51) and without (n = 21) respiratory distress syndrome (RDS). SP-A concentrations in samples collected after birth were significantly lower in RDS than in infants ventilated for other reasons than RDS (median 0.03 vs. 1.60 micrograms/ml). As a biochemical test to diagnose RDS early after birth, the sensitivity of measuring SP-A in tracheal aspirates was 87% and specificity 81%. SP-A content in tracheal aspirates of infants with RDS was monitored during the first 7 days of life. A significant (P less than 0.001) increase within the first 4 days was found in those infants who survived, whereas no such change was found in those infants who died.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
0340-6199
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
151
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
596-600
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:1505580-Enzyme-Linked Immunosorbent Assay,
pubmed-meshheading:1505580-Female,
pubmed-meshheading:1505580-Humans,
pubmed-meshheading:1505580-Infant, Newborn,
pubmed-meshheading:1505580-Male,
pubmed-meshheading:1505580-Proteolipids,
pubmed-meshheading:1505580-Pulmonary Surfactant-Associated Protein A,
pubmed-meshheading:1505580-Pulmonary Surfactant-Associated Proteins,
pubmed-meshheading:1505580-Pulmonary Surfactants,
pubmed-meshheading:1505580-Respiratory Distress Syndrome, Newborn,
pubmed-meshheading:1505580-Sensitivity and Specificity,
pubmed-meshheading:1505580-Trachea
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pubmed:year |
1992
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pubmed:articleTitle |
Surfactant protein A in the course of respiratory distress syndrome.
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pubmed:affiliation |
Department of Neonatology, University Children's Hospital, Free University Berlin, Federal Republic of Germany.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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