pubmed-article:15050644 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:15050644 | lifeskim:mentions | umls-concept:C0034721 | lld:lifeskim |
pubmed-article:15050644 | lifeskim:mentions | umls-concept:C0034693 | lld:lifeskim |
pubmed-article:15050644 | lifeskim:mentions | umls-concept:C0027882 | lld:lifeskim |
pubmed-article:15050644 | lifeskim:mentions | umls-concept:C0019564 | lld:lifeskim |
pubmed-article:15050644 | lifeskim:mentions | umls-concept:C0050587 | lld:lifeskim |
pubmed-article:15050644 | lifeskim:mentions | umls-concept:C0856984 | lld:lifeskim |
pubmed-article:15050644 | lifeskim:mentions | umls-concept:C0814034 | lld:lifeskim |
pubmed-article:15050644 | lifeskim:mentions | umls-concept:C1416614 | lld:lifeskim |
pubmed-article:15050644 | lifeskim:mentions | umls-concept:C0205263 | lld:lifeskim |
pubmed-article:15050644 | pubmed:issue | 8 | lld:pubmed |
pubmed-article:15050644 | pubmed:dateCreated | 2004-3-30 | lld:pubmed |
pubmed-article:15050644 | pubmed:abstractText | (S)-N-[1-(4-Cyclopropylmethyl-3,4-dihydro-2H-benzo[1,4]oxazin-6-yl)-ethyl]-3-(2-fluoro-phenyl)-acrylamide ((S)-2) was identified as a potent and efficacious KCNQ2 opener. This compound demonstrated significant activity in reducing neuronal hyperexcitability in rat hippocampal slices, and the inhibition mediated by (S)-2 was reversed by the KCNQ blocker linopirdine. | lld:pubmed |
pubmed-article:15050644 | pubmed:language | eng | lld:pubmed |
pubmed-article:15050644 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:15050644 | pubmed:citationSubset | IM | lld:pubmed |
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pubmed-article:15050644 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
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pubmed-article:15050644 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:15050644 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:15050644 | pubmed:month | Apr | lld:pubmed |
pubmed-article:15050644 | pubmed:issn | 0960-894X | lld:pubmed |
pubmed-article:15050644 | pubmed:author | pubmed-author:HugWW | lld:pubmed |
pubmed-article:15050644 | pubmed:author | pubmed-author:ChenJieJ | lld:pubmed |
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pubmed-article:15050644 | pubmed:author | pubmed-author:WuDedongD | lld:pubmed |
pubmed-article:15050644 | pubmed:author | pubmed-author:WuYong-JinYJ | lld:pubmed |
pubmed-article:15050644 | pubmed:author | pubmed-author:HeHuanH | lld:pubmed |
pubmed-article:15050644 | pubmed:author | pubmed-author:SunLi-QiangLQ | lld:pubmed |
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pubmed-article:15050644 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:15050644 | pubmed:day | 19 | lld:pubmed |
pubmed-article:15050644 | pubmed:volume | 14 | lld:pubmed |
pubmed-article:15050644 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:15050644 | pubmed:authorsComplete | Y | lld:pubmed |
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pubmed-article:15050644 | pubmed:dateRevised | 2005-11-17 | lld:pubmed |
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pubmed-article:15050644 | pubmed:year | 2004 | lld:pubmed |
pubmed-article:15050644 | pubmed:articleTitle | (S)-N-[1-(4-cyclopropylmethyl-3,4-dihydro-2H-benzo[1,4]oxazin-6-yl)-ethyl]-3-(2-fluoro-phenyl)-acrylamide is a potent and efficacious KCNQ2 opener which inhibits induced hyperexcitability of rat hippocampal neurons. | lld:pubmed |
pubmed-article:15050644 | pubmed:affiliation | Department of Neuroscience Chemistry, Bristol-Myers Squibb Pharmaceutical Research Institute, 5 Research Parkway, Wallingford, CT 06492, USA. yong-jin.wu@bms.com | lld:pubmed |
pubmed-article:15050644 | pubmed:publicationType | Journal Article | lld:pubmed |
http://linkedlifedata.com/r... | http://linkedlifedata.com/r... | pubmed-article:15050644 | lld:chembl |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:15050644 | lld:pubmed |