Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
2004-3-30
pubmed:abstractText
A key objective in neuroscience is to improve our understanding of the relationship between brain function and structure. We investigated this in the posterior visual pathways of healthy volunteers by applying functional magnetic resonance imaging (fMRI) and diffusion tensor imaging (DTI) with tractography. The optic radiations were segmented using the Probabilistic Index of Connectivity (PICo) tractography algorithm and extracted at several thresholds of connection confidence. The mean fractional anisotropy (FA) of the estimated tracts was found to correlate significantly with fMRI measures of visual cortex activity (induced by a photic stimulation paradigm). The results support the hypothesis that the visual cortical fMRI response is constrained by the external anatomical connections of the subserving optic radiations.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
1053-8119
pubmed:author
pubmed:issnType
Print
pubmed:volume
21
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1452-63
pubmed:dateRevised
2011-11-3
pubmed:meshHeading
pubmed-meshheading:15050570-Adult, pubmed-meshheading:15050570-Algorithms, pubmed-meshheading:15050570-Anisotropy, pubmed-meshheading:15050570-Brain Mapping, pubmed-meshheading:15050570-Diffusion Magnetic Resonance Imaging, pubmed-meshheading:15050570-Evoked Potentials, Visual, pubmed-meshheading:15050570-Female, pubmed-meshheading:15050570-Humans, pubmed-meshheading:15050570-Image Enhancement, pubmed-meshheading:15050570-Image Interpretation, Computer-Assisted, pubmed-meshheading:15050570-Linear Models, pubmed-meshheading:15050570-Magnetic Resonance Imaging, pubmed-meshheading:15050570-Male, pubmed-meshheading:15050570-Models, Statistical, pubmed-meshheading:15050570-Nerve Net, pubmed-meshheading:15050570-Optic Nerve, pubmed-meshheading:15050570-Oxygen, pubmed-meshheading:15050570-Photic Stimulation, pubmed-meshheading:15050570-Reproducibility of Results, pubmed-meshheading:15050570-Visual Cortex, pubmed-meshheading:15050570-Visual Pathways
pubmed:year
2004
pubmed:articleTitle
Characterizing function-structure relationships in the human visual system with functional MRI and diffusion tensor imaging.
pubmed:affiliation
NMR Research Unit, Institute of Neurology, University College London, London WC1N 3BG, UK.
pubmed:publicationType
Journal Article, Comparative Study, Research Support, Non-U.S. Gov't