|
rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0018328,
umls-concept:C0023150,
umls-concept:C0030933,
umls-concept:C0059039,
umls-concept:C0059040,
umls-concept:C0220866,
umls-concept:C0678640,
umls-concept:C1145667,
umls-concept:C1167622,
umls-concept:C1521828,
umls-concept:C2349209,
umls-concept:C2825311
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|
pubmed:issue |
2
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|
pubmed:dateCreated |
1992-9-16
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|
pubmed:abstractText |
The rate laws governing the exchange of guanine nucleotides bound to EF-Tu catalysed by EF-Ts are set out and the information that is available from various studies is analysed in terms of the laws. In particular the consequences of k-1 being equal to k-4 in the reaction sequence as set out below are examined in relation to results obtained by Hwang and Miller (J. Biol. Chem. 260, 11498-11502) and the contradiction these pose in relation to other published results. Measurement of on and off rate constants for binding of GTP to EF-Tu.EF-Ts and of the affinity of EF-Ts for EF-Tu.GTP should prove of importance in resolving discrepancies.
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pubmed:language |
eng
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pubmed:journal |
|
|
pubmed:citationSubset |
IM
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pubmed:chemical |
|
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pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
0158-5231
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|
pubmed:author |
|
|
pubmed:issnType |
Print
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pubmed:volume |
27
|
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pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
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pubmed:pagination |
311-9
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pubmed:dateRevised |
2000-12-18
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pubmed:meshHeading |
|
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pubmed:year |
1992
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pubmed:articleTitle |
Rate laws for the exchange of guanine nucleotides bound to EF-Tu catalysed by EF-Ts.
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|
pubmed:affiliation |
Department of Biochemistry, University of the Witwatersrand, Johannesburg, South Africa.
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pubmed:publicationType |
Journal Article
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