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rdf:type |
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lifeskim:mentions |
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pubmed:dateCreated |
2004-3-22
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pubmed:abstractText |
Downregulation of iNOS and NO is a pathway common for flavones and polyphenols, two distinct families of phytoalexins. Our data suggest that inhibition of the NO pathway could be one of the mechanisms involved in the proapoptotic properties of these phytoalexins in leukemia B-cells.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
0077-8923
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
1010
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
381-3
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:15033756-Antineoplastic Agents,
pubmed-meshheading:15033756-Apoptosis,
pubmed-meshheading:15033756-Cell Line, Tumor,
pubmed-meshheading:15033756-Flavonoids,
pubmed-meshheading:15033756-Gene Expression Regulation, Enzymologic,
pubmed-meshheading:15033756-Gene Expression Regulation, Neoplastic,
pubmed-meshheading:15033756-Humans,
pubmed-meshheading:15033756-Leukemia, Lymphocytic, Chronic, B-Cell,
pubmed-meshheading:15033756-Nitric Oxide Synthase,
pubmed-meshheading:15033756-Nitric Oxide Synthase Type II,
pubmed-meshheading:15033756-Phenols,
pubmed-meshheading:15033756-Piperidines,
pubmed-meshheading:15033756-Polyphenols
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pubmed:year |
2003
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pubmed:articleTitle |
The inducible NO synthase is downregulated during apoptosis of malignant cells from B-cell chronic lymphocytic leukemia induced by flavopiridol and polyphenols.
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pubmed:affiliation |
INSERM E355, Centre Biomédicale des Cordeliers, Paris, France. christian.billard@bhdc.jussieu.fr
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pubmed:publicationType |
Journal Article
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