Source:http://linkedlifedata.com/resource/pubmed/id/15033250
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
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pubmed:dateCreated |
2004-3-22
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pubmed:abstractText |
Estrogens regulate several biological processes involved in the pathogenesis of myocardial infarction. Catechol-O-methyltransferase (COMT) is a key enzyme in the degradation of estrogens. There is a functional polymorphism in the COMT gene (Val158Met), affecting the activity of the enzyme. We investigated if the low activity genotype of COMT is associated with an altered risk of myocardial infarction.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
0195-668X
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
25
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
386-91
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:15033250-Angiotensin-Converting Enzyme Inhibitors,
pubmed-meshheading:15033250-Captopril,
pubmed-meshheading:15033250-Case-Control Studies,
pubmed-meshheading:15033250-Catechol O-Methyltransferase,
pubmed-meshheading:15033250-Female,
pubmed-meshheading:15033250-Genotype,
pubmed-meshheading:15033250-Humans,
pubmed-meshheading:15033250-Hypertension,
pubmed-meshheading:15033250-Male,
pubmed-meshheading:15033250-Middle Aged,
pubmed-meshheading:15033250-Myocardial Infarction,
pubmed-meshheading:15033250-Polymorphism, Genetic,
pubmed-meshheading:15033250-Prospective Studies
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pubmed:year |
2004
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pubmed:articleTitle |
Association between the low activity genotype of catechol-O-methyltransferase and myocardial infarction in a hypertensive population.
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pubmed:affiliation |
Division of Clinical Pharmacology, Department of Internal Medicine, Sahlgrenska University Hospital, SE-413 45 Göteborg, Sweden.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't,
Multicenter Study
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