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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
4
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pubmed:dateCreated |
2004-4-15
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pubmed:abstractText |
Eosinophils are important cells in host immunity to infections by parasitic worms. Tissue-invasive helminthic parasites have been known to induce apoptosis of immune cells for their successful establishment in vivo. We have previously found that high doses of excretory-secreted products (ESP) secreted by lung fluke Paragonimus westermani newly excysted metacercariae (PwNEM), which cause pulmonary or extrapulmonary paragonimiasis in human beings, accelerate eosinophil cell death. However, little is known about the mechanism of eosinophil apoptosis induced by the Paragonimus-derived products.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Amino Acid Chloromethyl Ketones,
http://linkedlifedata.com/resource/pubmed/chemical/Antigens, Helminth,
http://linkedlifedata.com/resource/pubmed/chemical/CASP3 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Caspase 3,
http://linkedlifedata.com/resource/pubmed/chemical/Caspases,
http://linkedlifedata.com/resource/pubmed/chemical/Cysteine Proteinase Inhibitors,
http://linkedlifedata.com/resource/pubmed/chemical/Granulocyte-Macrophage...,
http://linkedlifedata.com/resource/pubmed/chemical/Interleukin-3,
http://linkedlifedata.com/resource/pubmed/chemical/Interleukin-5,
http://linkedlifedata.com/resource/pubmed/chemical/Phosphatidylserines,
http://linkedlifedata.com/resource/pubmed/chemical/benzyloxycarbonylvalyl-alanyl-aspart...
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pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
1018-2438
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pubmed:author |
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pubmed:copyrightInfo |
Copyright 2004 S. Karger AG, Basel
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pubmed:issnType |
Print
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pubmed:volume |
133
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
357-64
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:15031609-Amino Acid Chloromethyl Ketones,
pubmed-meshheading:15031609-Animals,
pubmed-meshheading:15031609-Antigens, Helminth,
pubmed-meshheading:15031609-Apoptosis,
pubmed-meshheading:15031609-Caspase 3,
pubmed-meshheading:15031609-Caspases,
pubmed-meshheading:15031609-Cell Survival,
pubmed-meshheading:15031609-Cysteine Proteinase Inhibitors,
pubmed-meshheading:15031609-Eosinophils,
pubmed-meshheading:15031609-Flow Cytometry,
pubmed-meshheading:15031609-Granulocyte-Macrophage Colony-Stimulating Factor,
pubmed-meshheading:15031609-Hot Temperature,
pubmed-meshheading:15031609-Humans,
pubmed-meshheading:15031609-Interleukin-3,
pubmed-meshheading:15031609-Interleukin-5,
pubmed-meshheading:15031609-Kinetics,
pubmed-meshheading:15031609-Paragonimiasis,
pubmed-meshheading:15031609-Paragonimus,
pubmed-meshheading:15031609-Phosphatidylserines
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pubmed:year |
2004
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pubmed:articleTitle |
Caspase-3-mediated apoptosis of human eosinophils by the tissue-invading helminth Paragonimus westermani.
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pubmed:affiliation |
Department of Parasitology, College of Medicine, Hanyang University, Seoul, Korea.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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