Source:http://linkedlifedata.com/resource/pubmed/id/15030491
Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
|
pubmed:dateCreated |
2004-3-19
|
pubmed:abstractText |
Generalized nonconvulsive absence seizures are characterized by the occurrence of synchronous and bilateral spike-and-wave discharges (SWDs) on electroencephalographic recordings, concomitant with behavioral arrest. The GAERS (genetic absence rats from Strasbourg) strain, a well-characterized inbred model for idiopathic generalized epilepsy, spontaneously develops EEG paroxysms that resemble those of typical absence seizures. The purpose of this study was to investigate the genetic control of SWD variables by using a combination of genetic analyses and electrophysiological measurements in an experimental cross derived from GAERS and Brown Norway (BN) rats.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:status |
MEDLINE
|
pubmed:month |
Apr
|
pubmed:issn |
0013-9580
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
45
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
301-8
|
pubmed:dateRevised |
2010-7-27
|
pubmed:meshHeading |
pubmed-meshheading:15030491-Action Potentials,
pubmed-meshheading:15030491-Animals,
pubmed-meshheading:15030491-Epilepsy, Absence,
pubmed-meshheading:15030491-Epilepsy, Generalized,
pubmed-meshheading:15030491-Female,
pubmed-meshheading:15030491-Male,
pubmed-meshheading:15030491-Multifactorial Inheritance,
pubmed-meshheading:15030491-Phenotype,
pubmed-meshheading:15030491-Quantitative Trait Loci,
pubmed-meshheading:15030491-Rats,
pubmed-meshheading:15030491-Rats, Inbred BN,
pubmed-meshheading:15030491-Rats, Inbred Strains,
pubmed-meshheading:15030491-Rats, Wistar
|
pubmed:year |
2004
|
pubmed:articleTitle |
Polygenic control of idiopathic generalized epilepsy phenotypes in the genetic absence rats from Strasbourg (GAERS).
|
pubmed:affiliation |
INSERM U398, Faculty of Medicine, Strasbourg, France.
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|