Linked Life Data

15028532

Source:http://linkedlifedata.com/resource/pubmed/id/15028532

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
2004-3-18
pubmed:abstractText
The sea lamprey (Petromyzon marinus L.) represents one of the two most ancient classes of vertebrates and possesses a functional hypothalamus-pituitary-gonadal axis. However, the presence and functionality of androgens in the sea lamprey remain elusive. Recently, 15alpha-hydroxytestosterone (15alpha-T) has been found in sea lamprey gonads and blood plasma. In this study we examined changes of circulatory concentrations of 15alpha-T in response to gonadotropin releasing hormone (GnRH) treatments. Plasma concentrations of 15alpha-T in sea lamprey increased 2-5 times for all GnRH-injected sea lamprey compared to controls (P < 0.001). However, there were no differences among responses: (1) to the two forms of GnRH (lamprey GnRH I or lamprey GnRH III), (2) to the doses delivered (50, 100, or 200 microg/kg), or (3) between post-injection sample intervals (8 or 24 h). Between lampreys from the Atlantic Ocean and Great Lakes sites, two of seven GnRH form and dosage comparisons showed between-site differences, but were not believed to represent an overall between-site difference. These are the first data to show a response of a C19 steroid to GnRH stimulation in sea lamprey.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
0016-6480
pubmed:author
pubmed:issnType
Print
pubmed:volume
136
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
276-81
pubmed:dateRevised
2008-7-11
pubmed:meshHeading
pubmed:year
2004
pubmed:articleTitle
15alpha-hydroxytestosterone induction by GnRH I and GnRH III in Atlantic and Great Lakes sea lamprey (Petromyzon marinus L.).
pubmed:affiliation
Department of Fisheries and Wildlife, 13 Natural Resources Building, Michigan State University, East Lansing, MI 48824-1222, USA.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, Non-P.H.S., Research Support, Non-U.S. Gov't