|
rdf:type |
|
|
lifeskim:mentions |
umls-concept:C1145667,
umls-concept:C1149274,
umls-concept:C1417006,
umls-concept:C1514562,
umls-concept:C1622186,
umls-concept:C1720655,
umls-concept:C1880389,
umls-concept:C1883204,
umls-concept:C1883221,
umls-concept:C1947974,
umls-concept:C2700455
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|
pubmed:issue |
5
|
|
pubmed:dateCreated |
2004-3-18
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|
pubmed:abstractText |
MAP2 and tau are abundant microtubule-associated proteins (MAPs) in neurons. The development of neuronal dendrites and axons requires a dynamic interaction between microtubules and actin filaments. MAPs represent good candidates to mediate such interactions. Although MAP2c and tau have similar, well-characterized microtubule binding activities, their actin interaction is poorly understood.
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pubmed:grant |
|
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pubmed:language |
eng
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pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Mar
|
|
pubmed:issn |
0960-9822
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|
pubmed:author |
|
|
pubmed:issnType |
Print
|
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pubmed:day |
9
|
|
pubmed:volume |
14
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
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pubmed:pagination |
363-71
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:15028210-Actins,
pubmed-meshheading:15028210-Animals,
pubmed-meshheading:15028210-Binding Sites,
pubmed-meshheading:15028210-Cells, Cultured,
pubmed-meshheading:15028210-Centrifugation,
pubmed-meshheading:15028210-DNA Primers,
pubmed-meshheading:15028210-Electrophoresis, Polyacrylamide Gel,
pubmed-meshheading:15028210-Immunohistochemistry,
pubmed-meshheading:15028210-Microscopy, Electron,
pubmed-meshheading:15028210-Microtubule-Associated Proteins,
pubmed-meshheading:15028210-Microtubules,
pubmed-meshheading:15028210-Morphogenesis,
pubmed-meshheading:15028210-Neurons,
pubmed-meshheading:15028210-Recombinant Fusion Proteins,
pubmed-meshheading:15028210-tau Proteins
|
|
pubmed:year |
2004
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|
pubmed:articleTitle |
MAP2c, but not tau, binds and bundles F-actin via its microtubule binding domain.
|
|
pubmed:affiliation |
Department of Cell Biology and Institute for Childhood and Neglected Diseases, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA.
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|
pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
|
