Source:http://linkedlifedata.com/resource/pubmed/id/15025821
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
2004-3-17
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pubmed:abstractText |
The biological actions of lipopolysaccharides (LPSs) from Sinorhizobium meliloti, Mesorhizobium loti and Escherichia coli were compared. In biological activities including lethality, production of tumor necrosis factor (TNF)-alpha and nitric oxide (NO), adjuvant action and Limulus activity, LPS from S. meliloti exhibited stronger actions than LPS from M. loti, but had a weaker action than LPS from E. coli. On the other hand, M. loti LPS showed a higher activity to activate human complement than S. meliloti LPS. Further, there was a significant difference in polymyxin B binding between S. meliloti LPS and M. loti LPS, suggesting a difference in the lipid A structure. LPSs from S. meliloti and M. loti seem to exhibit characteristic biological actions that may be dependent on the difference in the lipid A structure.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0968-0519
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
10
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
25-31
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:15025821-Animals,
pubmed-meshheading:15025821-Biological Assay,
pubmed-meshheading:15025821-Escherichia coli,
pubmed-meshheading:15025821-Horseshoe Crabs,
pubmed-meshheading:15025821-Lipopolysaccharides,
pubmed-meshheading:15025821-Nitric Oxide,
pubmed-meshheading:15025821-Proteobacteria,
pubmed-meshheading:15025821-Sinorhizobium,
pubmed-meshheading:15025821-Structure-Activity Relationship,
pubmed-meshheading:15025821-Tumor Necrosis Factor-alpha
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pubmed:year |
2004
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pubmed:articleTitle |
Characteristic biological activities of lipopolysaccharides from Sinorhizobium and Mesorhizobium.
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pubmed:affiliation |
Department of Natural Science Informatics, School of Informatics and Sciences & Department of Microbiology and Immunology, Aichi Medical University School of Medicine, Nagakute, Aichi, Japan.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
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