Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
2004-3-17
pubmed:databankReference
pubmed:abstractText
PROWESS (Recombinant Human Activated Protein C Worldwide Evaluation in Severe Sepsis) was a phase III, randomized, double blind, placebo controlled, multicenter trial conducted in patients with severe sepsis from 164 medical centers. Here we report data collected at study entry for 1690 patients and over the following 7 days for the 840 patients who received placebo (in addition to usual standard of care).
pubmed:commentsCorrections
http://linkedlifedata.com/resource/pubmed/commentcorrection/15025782-10446824, http://linkedlifedata.com/resource/pubmed/commentcorrection/15025782-10605772, http://linkedlifedata.com/resource/pubmed/commentcorrection/15025782-10921542, http://linkedlifedata.com/resource/pubmed/commentcorrection/15025782-11236773, http://linkedlifedata.com/resource/pubmed/commentcorrection/15025782-11445675, http://linkedlifedata.com/resource/pubmed/commentcorrection/15025782-11816725, http://linkedlifedata.com/resource/pubmed/commentcorrection/15025782-12000765, http://linkedlifedata.com/resource/pubmed/commentcorrection/15025782-12117955, http://linkedlifedata.com/resource/pubmed/commentcorrection/15025782-12378655, http://linkedlifedata.com/resource/pubmed/commentcorrection/15025782-1303622, http://linkedlifedata.com/resource/pubmed/commentcorrection/15025782-15025767, http://linkedlifedata.com/resource/pubmed/commentcorrection/15025782-2502362, http://linkedlifedata.com/resource/pubmed/commentcorrection/15025782-5677719, http://linkedlifedata.com/resource/pubmed/commentcorrection/15025782-7674528, http://linkedlifedata.com/resource/pubmed/commentcorrection/15025782-7850574, http://linkedlifedata.com/resource/pubmed/commentcorrection/15025782-8486040, http://linkedlifedata.com/resource/pubmed/commentcorrection/15025782-8704245, http://linkedlifedata.com/resource/pubmed/commentcorrection/15025782-9299971, http://linkedlifedata.com/resource/pubmed/commentcorrection/15025782-9875912
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
1466-609X
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
8
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
R82-90
pubmed:dateRevised
2009-11-18
pubmed:meshHeading
pubmed-meshheading:15025782-APACHE, pubmed-meshheading:15025782-Biological Markers, pubmed-meshheading:15025782-Blood Coagulation Disorders, pubmed-meshheading:15025782-C-Reactive Protein, pubmed-meshheading:15025782-Disseminated Intravascular Coagulation, pubmed-meshheading:15025782-Endothelium, pubmed-meshheading:15025782-Fibrin, pubmed-meshheading:15025782-Fibrinolysis, pubmed-meshheading:15025782-Humans, pubmed-meshheading:15025782-Inflammation, pubmed-meshheading:15025782-Partial Thromboplastin Time, pubmed-meshheading:15025782-Placebos, pubmed-meshheading:15025782-Prognosis, pubmed-meshheading:15025782-Protein C, pubmed-meshheading:15025782-Recombinant Proteins, pubmed-meshheading:15025782-Sensitivity and Specificity, pubmed-meshheading:15025782-Sepsis, pubmed-meshheading:15025782-Severity of Illness Index, pubmed-meshheading:15025782-Surgical Procedures, Operative, pubmed-meshheading:15025782-Surgical Wound Infection
pubmed:year
2004
pubmed:articleTitle
Universal changes in biomarkers of coagulation and inflammation occur in patients with severe sepsis, regardless of causative micro-organism [ISRCTN74215569].
pubmed:affiliation
Department of Medicine, Physiology and Biophysics, University of Oklahoma Health Science Center, and Cardiovascular Biology, Oklahoma Medical Research Foundation, Oklahoma City, Oklahoma, USA.
pubmed:publicationType
Journal Article, Clinical Trial, Randomized Controlled Trial, Research Support, Non-U.S. Gov't, Multicenter Study, Clinical Trial, Phase III