Source:http://linkedlifedata.com/resource/pubmed/id/15025358
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
4
|
| pubmed:dateCreated |
2004-3-17
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| pubmed:abstractText |
431 patients with thrombosis of different venous system were evaluated for underlying acquired and inherited prothrombotic states. Associated acquired risk factors were observed to be present in 28.7% patients and possible inherited in 32.3%, in the rest, no cause could be identified. Major acquired risk factors included coexistence of liver disease (12.2%), oral contraceptives (4.1%), puerperium (2.5%), malignancy (2.3%) and lupus anticoagulant (2%). Low levels of protein C were detected in 21.1% and of which 11.3% were attributed to acquired factors. Protein S deficiency was found in 19.0% and of these 10.4% cases were associated with acquired risk factors. Antithrombin III (AT III) deficiency was detected in 6.4% of patients, of which 4.8% were secondary to acquired factors. In the rest, deficiency of protein C, protein S and AT III were attributed to inherited factors as no associated acquired risk factor was present. Activated protein C resistance (APC-R) was present in 12.5% cases.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Oct
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| pubmed:issn |
0377-4929
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| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
46
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| pubmed:owner |
NLM
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| pubmed:authorsComplete |
Y
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| pubmed:pagination |
621-4
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| pubmed:dateRevised |
2004-11-17
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| pubmed:meshHeading |
pubmed-meshheading:15025358-Adolescent,
pubmed-meshheading:15025358-Adult,
pubmed-meshheading:15025358-Aged,
pubmed-meshheading:15025358-Aged, 80 and over,
pubmed-meshheading:15025358-Antithrombin III Deficiency,
pubmed-meshheading:15025358-Child,
pubmed-meshheading:15025358-Contraceptives, Oral,
pubmed-meshheading:15025358-Female,
pubmed-meshheading:15025358-Humans,
pubmed-meshheading:15025358-India,
pubmed-meshheading:15025358-Liver Diseases,
pubmed-meshheading:15025358-Male,
pubmed-meshheading:15025358-Middle Aged,
pubmed-meshheading:15025358-Pregnancy,
pubmed-meshheading:15025358-Pregnancy Complications,
pubmed-meshheading:15025358-Protein C Deficiency,
pubmed-meshheading:15025358-Protein S Deficiency,
pubmed-meshheading:15025358-Risk Factors,
pubmed-meshheading:15025358-Venous Thrombosis
|
| pubmed:year |
2003
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| pubmed:articleTitle |
Venous thrombosis: prevalence of prothrombotic defects in north Indian population.
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| pubmed:affiliation |
Department of Hematology, All India Institute of Medical Sciences, New Delhi.
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| pubmed:publicationType |
Journal Article
|