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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
11
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pubmed:dateCreated |
2004-3-23
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pubmed:abstractText |
The antiplatelet effect of clopidogrel may be attenuated by short-term coadministration of lipophilic statins. We investigated whether the coadministration of atorvastatin for 5 weeks in patients with acute coronary syndromes (ACS) could affect the antiplatelet potency of clopidogrel.
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Adenosine Diphosphate,
http://linkedlifedata.com/resource/pubmed/chemical/CD40 Ligand,
http://linkedlifedata.com/resource/pubmed/chemical/CYP3A protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Cytochrome P-450 CYP3A,
http://linkedlifedata.com/resource/pubmed/chemical/Cytochrome P-450 Enzyme System,
http://linkedlifedata.com/resource/pubmed/chemical/Heptanoic Acids,
http://linkedlifedata.com/resource/pubmed/chemical/Hydroxymethylglutaryl-CoA...,
http://linkedlifedata.com/resource/pubmed/chemical/P-Selectin,
http://linkedlifedata.com/resource/pubmed/chemical/Peptide Fragments,
http://linkedlifedata.com/resource/pubmed/chemical/Platelet Aggregation Inhibitors,
http://linkedlifedata.com/resource/pubmed/chemical/Pravastatin,
http://linkedlifedata.com/resource/pubmed/chemical/Pyrroles,
http://linkedlifedata.com/resource/pubmed/chemical/Ticlopidine,
http://linkedlifedata.com/resource/pubmed/chemical/atorvastatin,
http://linkedlifedata.com/resource/pubmed/chemical/clopidogrel,
http://linkedlifedata.com/resource/pubmed/chemical/thrombin receptor peptide (42-55)
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pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
1524-4539
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:day |
23
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pubmed:volume |
109
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1335-8
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pubmed:dateRevised |
2010-11-18
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pubmed:meshHeading |
pubmed-meshheading:15023882-Acute Disease,
pubmed-meshheading:15023882-Adenosine Diphosphate,
pubmed-meshheading:15023882-Aged,
pubmed-meshheading:15023882-Angioplasty, Balloon, Coronary,
pubmed-meshheading:15023882-CD40 Ligand,
pubmed-meshheading:15023882-Combined Modality Therapy,
pubmed-meshheading:15023882-Coronary Disease,
pubmed-meshheading:15023882-Cytochrome P-450 CYP3A,
pubmed-meshheading:15023882-Cytochrome P-450 Enzyme System,
pubmed-meshheading:15023882-Drug Administration Schedule,
pubmed-meshheading:15023882-Drug Interactions,
pubmed-meshheading:15023882-Female,
pubmed-meshheading:15023882-Heptanoic Acids,
pubmed-meshheading:15023882-Humans,
pubmed-meshheading:15023882-Hydroxymethylglutaryl-CoA Reductase Inhibitors,
pubmed-meshheading:15023882-Male,
pubmed-meshheading:15023882-Metabolic Detoxication, Drug,
pubmed-meshheading:15023882-Middle Aged,
pubmed-meshheading:15023882-P-Selectin,
pubmed-meshheading:15023882-Peptide Fragments,
pubmed-meshheading:15023882-Platelet Aggregation,
pubmed-meshheading:15023882-Platelet Aggregation Inhibitors,
pubmed-meshheading:15023882-Pravastatin,
pubmed-meshheading:15023882-Pyrroles,
pubmed-meshheading:15023882-Stents,
pubmed-meshheading:15023882-Ticlopidine,
pubmed-meshheading:15023882-Treatment Outcome
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pubmed:year |
2004
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pubmed:articleTitle |
Atorvastatin does not affect the antiplatelet potency of clopidogrel when it is administered concomitantly for 5 weeks in patients with acute coronary syndromes.
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pubmed:affiliation |
Laboratory of Biochemistry, Department of Chemistry, University of Ioannina, Ioannina, Greece.
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Randomized Controlled Trial
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