|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
2
|
|
pubmed:dateCreated |
2004-3-16
|
|
pubmed:abstractText |
The risk of haemophiliacs contracting variant Creutzfeldt-Jakob disease (vCJD) via treatment with factor VIII concentrates is not known. Therefore, in order to determine the extent to which the vCJD agent might be removed during the preparation of factor VIII concentrate, the partitioning of a bovine spongiform encephalopathy (BSE)-derived agent was measured over the main purification step used to prepare the Scottish National Blood Transfusion Service high-purity factor VIII concentrate (Liberate).
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Feb
|
|
pubmed:issn |
0042-9007
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
86
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
92-9
|
|
pubmed:dateRevised |
2006-11-15
|
|
pubmed:meshHeading |
pubmed-meshheading:15023177-Adsorption,
pubmed-meshheading:15023177-Animals,
pubmed-meshheading:15023177-Biological Assay,
pubmed-meshheading:15023177-Brain Chemistry,
pubmed-meshheading:15023177-Cattle,
pubmed-meshheading:15023177-Chromatography, Ion Exchange,
pubmed-meshheading:15023177-Creutzfeldt-Jakob Syndrome,
pubmed-meshheading:15023177-Encephalopathy, Bovine Spongiform,
pubmed-meshheading:15023177-Ethanolamines,
pubmed-meshheading:15023177-Factor VIII,
pubmed-meshheading:15023177-Fibrinogen,
pubmed-meshheading:15023177-Humans,
pubmed-meshheading:15023177-Mice,
pubmed-meshheading:15023177-Mice, Inbred Strains,
pubmed-meshheading:15023177-Microsomes,
pubmed-meshheading:15023177-Polymers,
pubmed-meshheading:15023177-PrPSc Proteins,
pubmed-meshheading:15023177-Sensitivity and Specificity,
pubmed-meshheading:15023177-Sodium Chloride,
pubmed-meshheading:15023177-Sodium Hydroxide,
pubmed-meshheading:15023177-Solvents,
pubmed-meshheading:15023177-Virulence
|
|
pubmed:year |
2004
|
|
pubmed:articleTitle |
Distribution of a bovine spongiform encephalopathy-derived agent over ion-exchange chromatography used in the preparation of concentrates of fibrinogen and factor VIII.
|
|
pubmed:affiliation |
Scottish National Blood Transfusion Service, Edinburgh, UK. peter.foster@snbts.csa.scot.nhs.uk
|
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Evaluation Studies
|
