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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3
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pubmed:dateCreated |
2004-3-15
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pubmed:abstractText |
Familial aggregation has been recognized in patients with several lymphoid neoplasms, but the genetic basis for this familial clustering is not known. Germ-line mutations in the ataxia-telangiectasia mutated (ATM) and CHK2 genes have been detected in patients with mantle cell lymphoma (MCL), suggesting a potential role of these genes in genetic predisposition to these tumors. However, no familial association has been previously recognized in MCL.
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
1592-8721
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
89
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
314-9
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pubmed:dateRevised |
2011-11-2
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pubmed:meshHeading |
pubmed-meshheading:15020270-Adult,
pubmed-meshheading:15020270-Aged,
pubmed-meshheading:15020270-Cell Cycle Proteins,
pubmed-meshheading:15020270-DNA Damage,
pubmed-meshheading:15020270-DNA-Binding Proteins,
pubmed-meshheading:15020270-Family Health,
pubmed-meshheading:15020270-Female,
pubmed-meshheading:15020270-Genes, p53,
pubmed-meshheading:15020270-Genetic Predisposition to Disease,
pubmed-meshheading:15020270-Humans,
pubmed-meshheading:15020270-Lymphoma,
pubmed-meshheading:15020270-Lymphoma, Mantle-Cell,
pubmed-meshheading:15020270-Male,
pubmed-meshheading:15020270-Middle Aged,
pubmed-meshheading:15020270-Mutation,
pubmed-meshheading:15020270-Pedigree,
pubmed-meshheading:15020270-Protein Kinases,
pubmed-meshheading:15020270-Protein-Serine-Threonine Kinases,
pubmed-meshheading:15020270-Tumor Suppressor Proteins
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pubmed:year |
2004
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pubmed:articleTitle |
Familial lymphoid neoplasms in patients with mantle cell lymphoma.
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pubmed:affiliation |
Hematopathology Unit, Department of Pathology, Hospital Clinic, Institut d'Investigacions Biomèdiques August Pi i Sunyer, University of Barcelona, Spain.
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pubmed:publicationType |
Journal Article,
Case Reports,
Research Support, Non-U.S. Gov't
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