Switch to
| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
2
|
| pubmed:dateCreated |
1992-9-16
|
| pubmed:abstractText |
The chromosome constitutions of stimulated lymphocytes from 50 B-cell chronic lymphocytic leukemia patients were studied using different stimulation systems, i.e., TPA alone or associated with different cytokines. Adequate metaphases were obtained in 44 subjects (88%). Among 20 patients with abnormal karyotypes (45.5%), 7 had trisomy 12. The most frequent structural abnormality was a 14q+ resulting from translocations including one t(11;14) and two t(14;17), while deletions on the long arms of chromosomes 6 and 13 constituted a second common alteration. The most important finding in this series was the recurrence of a t(18;22) observed in two cases.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:status |
MEDLINE
|
| pubmed:author | |
| pubmed:volume |
34
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
175-82
|
| pubmed:dateRevised |
2007-11-15
|
| pubmed:meshHeading |
pubmed-meshheading:1502024-Adult,
pubmed-meshheading:1502024-Aged,
pubmed-meshheading:1502024-Aged, 80 and over,
pubmed-meshheading:1502024-Cells, Cultured,
pubmed-meshheading:1502024-Chromosome Aberrations,
pubmed-meshheading:1502024-Chromosome Disorders,
pubmed-meshheading:1502024-Female,
pubmed-meshheading:1502024-Humans,
pubmed-meshheading:1502024-Karyotyping,
pubmed-meshheading:1502024-Leukemia, Lymphocytic, Chronic, B-Cell,
pubmed-meshheading:1502024-Lymphocyte Activation,
pubmed-meshheading:1502024-Male,
pubmed-meshheading:1502024-Middle Aged
|
| pubmed:year |
1992
|
| pubmed:articleTitle |
Chromosome studies in stimulated lymphocytes of 50 patients with B-cell chronic lymphocytic leukemia.
|
| pubmed:affiliation |
Département d'Hématologie, Hôpital Nord, St Priest en Jarez, France.
|
| pubmed:publicationType |
Journal Article
|