Linked Life Data

15018076

Source:http://linkedlifedata.com/resource/pubmed/id/15018076

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
20
pubmed:dateCreated
2004-3-15
pubmed:abstractText
Prostate cancer had a development predominantly at peripheral gland and stay for a long time asymptomatic without clinical symptoms. When the cancer is symptomatic, it is often translate an advanced stage. The symptoms of prostate cancer are not specifics: urinary troubles, compression of iliac vessels or bone metastases pain. The digital rectal examination highlight an induration nodule, irregular and painless. The probability to have a cancer increase with the rate of the prostate specific antigen (PSA). Some others situations can increase the rate of PSA: benign prostatic hyperplasia, prostatitis, bladder catheterisation, urinary retention, endoscopic examination. The ratio of free-PSA/total-PSA (fPSA/tPSA) permits a best discrimination between benign prostatic hyperplasia and prostate cancer The more fPSA/tPSA ratio is low, the more the risk of prostate cancer is high. Prostate cancer is suspected with the digital rectal examination and the rate of PSA but the diagnosis is made by histological examination (the tissue samples are took by transrectal ultrasound-guided biopsies). The staging of disease must be realised according to the risk of metastasis appreciated by clinical stage, rate of PSA and Gleason score.
pubmed:language
fre
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0035-2640
pubmed:author
pubmed:issnType
Print
pubmed:day
31
pubmed:volume
53
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
2229-36
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
2003
pubmed:articleTitle
[Prostate specific antigen and diagnosis of prostate cancer].
pubmed:affiliation
Clinique uroloqique, CHU Hôtel-Dieu, 44093 Nantes 01. jrigaud@chu-nantes.fr
pubmed:publicationType
Journal Article, Comparative Study, English Abstract