|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
1
|
|
pubmed:dateCreated |
2004-3-12
|
|
pubmed:abstractText |
p53 retarded tumor growth by several known mechanisms, including suppression of cell proliferation and inhibition of tumor angiogenesis. Vascular endothelial growth factors (VEGF) and angiopoietins (Ang-1, Ang-2) are major angiogeneic modulators. The current study examined the effect of p53 on the expression of these factors in conjunction with tumor growth and vascular formation.
|
|
pubmed:commentsCorrections |
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:issn |
0250-7005
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
24
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
1-10
|
|
pubmed:dateRevised |
2009-11-19
|
|
pubmed:meshHeading |
pubmed-meshheading:15015569-Angiogenic Proteins,
pubmed-meshheading:15015569-Angiopoietin-1,
pubmed-meshheading:15015569-Angiopoietin-2,
pubmed-meshheading:15015569-Animals,
pubmed-meshheading:15015569-Brain Neoplasms,
pubmed-meshheading:15015569-Cell Line, Tumor,
pubmed-meshheading:15015569-DNA, Complementary,
pubmed-meshheading:15015569-Genes, p53,
pubmed-meshheading:15015569-Glioblastoma,
pubmed-meshheading:15015569-Humans,
pubmed-meshheading:15015569-Immunohistochemistry,
pubmed-meshheading:15015569-Neoplasm Transplantation,
pubmed-meshheading:15015569-Neovascularization, Pathologic,
pubmed-meshheading:15015569-Rats,
pubmed-meshheading:15015569-Rats, Sprague-Dawley,
pubmed-meshheading:15015569-Receptor, TIE-2,
pubmed-meshheading:15015569-Reverse Transcriptase Polymerase Chain Reaction,
pubmed-meshheading:15015569-Transfection,
pubmed-meshheading:15015569-Tumor Suppressor Protein p53,
pubmed-meshheading:15015569-Vascular Endothelial Growth Factor A
|
|
pubmed:articleTitle |
Effects of tumor suppressor gene (p53) on brain tumor angiogenesis and expression of angiogenic modulators.
|
|
pubmed:affiliation |
Department of Neurosurgery, Stanford University School of Medicine, Stanford, CA, USA. vkt@stanford.edu
|
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|
