Source:http://linkedlifedata.com/resource/pubmed/id/15015186
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
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pubmed:dateCreated |
2004-3-11
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pubmed:abstractText |
OBJECTIVES: The endovascular aneurysm repair (EVAR) trials aim to assess the efficacy of EVAR in the treatment of AAA in terms of mortality, quality of life, durability and cost-effectiveness. DESIGN: Male and female patients aged at least 60 years with an AAA diameter measuring at least 5.5 cm on a computed tomography (CT) scan are assessed for anatomical suitability for EVAR. Suitable patients are offered entry either into EVAR Trial 1 if they are considered fit for conventional open repair or EVAR Trial 2 if they are considered unfit. EVAR 1 randomly allocates patients to EVAR or open repair and EVAR 2 randomly allocates patients to EVAR with best medical treatment or best medical treatment alone. Target recruitment for EVAR Trials 1 and 2 is 900 and 280 patients, respectively. PROGRESS: Recruitment began in September 1999 and there are currently 40 UK centres participating in the trials. Monthly targets are being exceeded in EVAR Trial 1 with 1037 patients randomised by October 2003. EVAR Trial 2 is also meeting monthly targets with a total of 319 patients randomised. When recruitment closes in December 2003 patients will need to be followed for at least 1 year from their operation. Publication of full results for both trials is expected in mid 2005.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
1078-5884
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
27
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
372-81
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:15015186-Aortic Aneurysm, Abdominal,
pubmed-meshheading:15015186-Blood Vessel Prosthesis Implantation,
pubmed-meshheading:15015186-Female,
pubmed-meshheading:15015186-Great Britain,
pubmed-meshheading:15015186-Humans,
pubmed-meshheading:15015186-Male,
pubmed-meshheading:15015186-Middle Aged,
pubmed-meshheading:15015186-Multicenter Studies as Topic,
pubmed-meshheading:15015186-Patient Selection,
pubmed-meshheading:15015186-Randomized Controlled Trials as Topic,
pubmed-meshheading:15015186-Regression Analysis,
pubmed-meshheading:15015186-Research Design
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pubmed:year |
2004
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pubmed:articleTitle |
The UK Endovascular Aneurysm Repair (EVAR) trials: design, methodology and progress.
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pubmed:affiliation |
Imperial College of Science, Technology and Medicine, London, UK.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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