Source:http://linkedlifedata.com/resource/pubmed/id/15012015
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
2004-3-11
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pubmed:abstractText |
The individual leaves of a multileaf collimator (MLC) have a tongue-and-groove or stepped-edge design to minimize leakage radiation between adjacent leaves. This design element has a drawback in that it creates areas of underdosages in intensity-modulated photon beams unless a leaf trajectory is specifically designed such that for any two adjacent leaf pairs, the direct exposure under the tongue-and-groove is equal to the lower of the direct exposures of the leaf pairs. In this work, we present a systematic study of the optimization of a leaf sequencing algorithm for segmental multileaf collimator beam delivery that completely eliminates areas of underdosages due to tongue-and-groove or stepped-edge design of the MLC. Simultaneous elimination of tongue-and-groove effect and leaf interdigitation is also studied. This is an extension of our previous work (Kamath et al 2003a Phys. Med. Biol. 48 307) in which we described a leaf sequencing algorithm that is optimal for monitor unit (MU) efficiency under most common leaf movement constraints that include minimum leaf separation. Compared to our previously published algorithm (without constraints), the new algorithms increase the number of sub-fields by approximately 21% and 25%, respectively, but are optimal in MU efficiency for unidirectional schedules.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0031-9155
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
7
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pubmed:volume |
49
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
N7-19
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:15012015-Algorithms,
pubmed-meshheading:15012015-Motion,
pubmed-meshheading:15012015-Quality Control,
pubmed-meshheading:15012015-Radiometry,
pubmed-meshheading:15012015-Radiotherapy, Computer-Assisted,
pubmed-meshheading:15012015-Radiotherapy, Conformal,
pubmed-meshheading:15012015-Radiotherapy Dosage,
pubmed-meshheading:15012015-Radiotherapy Planning, Computer-Assisted,
pubmed-meshheading:15012015-Reproducibility of Results,
pubmed-meshheading:15012015-Sensitivity and Specificity
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pubmed:year |
2004
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pubmed:articleTitle |
Optimal leaf sequencing with elimination of tongue-and-groove underdosage.
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pubmed:affiliation |
Department of Computer and Information Science and Engineering, University of Florida, Gainesville, FL, USA. srkamath@cise.ufl.edu
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, U.S. Gov't, P.H.S.,
Evaluation Studies,
Validation Studies
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