Source:http://linkedlifedata.com/resource/pubmed/id/15009816
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
2
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| pubmed:dateCreated |
2004-3-10
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| pubmed:abstractText |
Seven Japanese patients on maintenance hemodialysis who were comorbid with mild depression were medicated with 50 mg/day fluvoxamine maleate for 28 days. Effectiveness was obtained in four out of seven patients (57%). The plasma fluvoxamine concentrations were examined in three patients. The plasma fuvoxamine concentration decreased by 22% by hemodialysis. There is a tendency for the dialyzed rate of fluvoxamine to become lower if the plasma albumin concentration is higher. The half-life of fluvoxamine was possibly shortened more in the patient with hypoalbuminaemia. The plasma fluvoxamine concentration reached a steady state 8 days after the start of medication and thereafter. The time required to reach steady state was lengthened when compared with the results in normal Japanese volunteers.
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| pubmed:language |
eng
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| pubmed:journal | |
| pubmed:citationSubset |
IM
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| pubmed:chemical | |
| pubmed:status |
MEDLINE
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| pubmed:month |
Apr
|
| pubmed:issn |
1323-1316
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| pubmed:author | |
| pubmed:issnType |
Print
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| pubmed:volume |
58
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| pubmed:owner |
NLM
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| pubmed:authorsComplete |
Y
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| pubmed:pagination |
133-7
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| pubmed:dateRevised |
2004-11-17
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| pubmed:meshHeading |
pubmed-meshheading:15009816-Antidepressive Agents, Second-Generation,
pubmed-meshheading:15009816-Biological Availability,
pubmed-meshheading:15009816-Depressive Disorder,
pubmed-meshheading:15009816-Diabetic Nephropathies,
pubmed-meshheading:15009816-Dose-Response Relationship, Drug,
pubmed-meshheading:15009816-Drug Administration Schedule,
pubmed-meshheading:15009816-Female,
pubmed-meshheading:15009816-Fluvoxamine,
pubmed-meshheading:15009816-Half-Life,
pubmed-meshheading:15009816-Humans,
pubmed-meshheading:15009816-Japan,
pubmed-meshheading:15009816-Kidney Failure, Chronic,
pubmed-meshheading:15009816-Male,
pubmed-meshheading:15009816-Metabolic Clearance Rate,
pubmed-meshheading:15009816-Middle Aged,
pubmed-meshheading:15009816-Personality Inventory,
pubmed-meshheading:15009816-Renal Dialysis,
pubmed-meshheading:15009816-Treatment Outcome
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| pubmed:year |
2004
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| pubmed:articleTitle |
Efficacy and pharmacokinetics of fluvoxamine maleate in patients with mild depression undergoing hemodialysis.
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| pubmed:affiliation |
Department of Psychiatry, Tokyo Women's Medical University and Tsuruta Clinic, Tokyo, Japan. tkano@psy.twmu.ac.jp
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| pubmed:publicationType |
Journal Article
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