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pubmed-article:15009176pubmed:abstractTextSingle nucleotide polymorphisms in the tumour necrosis factor alpha (TNF-alpha) promoter region may modulate TNF-alpha gene transcriptional activity by modifying the binding of transcription factors. Here we confirm that a specific DNA complex binds preferentially the variant TNF2 allele in various cell types and demonstrate that activating protein (AP)-2, myeloid zinc finger gene 1 (MZF-1) and Sp1 are not involved in this complex.lld:pubmed
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pubmed-article:15009176pubmed:articleTitleAllele-specific binding to the -308 single nucleotide polymorphism site in the tumour necrosis factor-alpha promoter.lld:pubmed
pubmed-article:15009176pubmed:affiliationEquipe d'Accueil 3737 Pathologie des Cellules Lymphoïdes, Claude Bernard University, Lyon, France.lld:pubmed
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