Source:http://linkedlifedata.com/resource/pubmed/id/15006378
Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
6
|
pubmed:dateCreated |
2004-3-9
|
pubmed:abstractText |
A library of pentapeptides containing the sequence -Y-X-Y- based on rational design was screened with six different lectins. Sequences were identified that modulate galectin binding to its natural carbohydrate ligand. SPR showed inhibition values 2-3 times stronger than galactose and NMR studies suggested real carbohydrate mimicry.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Mar
|
pubmed:issn |
0960-894X
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:day |
22
|
pubmed:volume |
14
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
1437-40
|
pubmed:dateRevised |
2006-11-15
|
pubmed:meshHeading |
pubmed-meshheading:15006378-Amino Acid Sequence,
pubmed-meshheading:15006378-Dose-Response Relationship, Drug,
pubmed-meshheading:15006378-Galactose,
pubmed-meshheading:15006378-Lectins,
pubmed-meshheading:15006378-Ligands,
pubmed-meshheading:15006378-Molecular Sequence Data,
pubmed-meshheading:15006378-Oligopeptides,
pubmed-meshheading:15006378-Protein Binding
|
pubmed:year |
2004
|
pubmed:articleTitle |
Interference of the galactose-dependent binding of lectins by novel pentapeptide ligands.
|
pubmed:affiliation |
Utrecht Institute for Pharmaceutical Sciences, Department of Medicinal Chemistry, Utrecht University, PO Box 80082, 3508 TB Utrecht, The Netherlands.
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|