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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
6
|
| pubmed:dateCreated |
1992-9-14
|
| pubmed:abstractText |
A novel compound depudecin inducing the flat phenotype of ras- and src- transformed NIH3T3 cells at a concentration of 1 microgram/ml was isolated from the culture broth of Alternaria brassicicola. Based on its spectroscopic characteristics and X-ray crystallographic analysis of its bis-(1S)-(-)-camphanate, the structure of depudecin was determined to be (2R,3S,4S,5E,7S,8S,9R)-2,9- dihydroxy-3,4;7,8-diepoxy-undeca-5,10-diene.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Jun
|
| pubmed:issn |
0021-8820
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
45
|
| pubmed:geneSymbol |
ras,
src
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
N
|
| pubmed:pagination |
879-85
|
| pubmed:dateRevised |
2003-11-14
|
| pubmed:meshHeading |
pubmed-meshheading:1500354-3T3 Cells,
pubmed-meshheading:1500354-Alkadienes,
pubmed-meshheading:1500354-Alternaria,
pubmed-meshheading:1500354-Animals,
pubmed-meshheading:1500354-Cell Transformation, Neoplastic,
pubmed-meshheading:1500354-Epoxy Compounds,
pubmed-meshheading:1500354-Fatty Alcohols,
pubmed-meshheading:1500354-Fermentation,
pubmed-meshheading:1500354-Genes, ras,
pubmed-meshheading:1500354-Genes, src,
pubmed-meshheading:1500354-Mice,
pubmed-meshheading:1500354-Phenotype
|
| pubmed:year |
1992
|
| pubmed:articleTitle |
Depudecin: a novel compound inducing the flat phenotype of NIH3T3 cells doubly transformed by ras- and src-oncogene, produced by Alternaria brassicicola.
|
| pubmed:affiliation |
Shionogi Research Laboratories, Shionogi & Co., Ltd., Osaka, Japan.
|
| pubmed:publicationType |
Journal Article
|