Source:http://linkedlifedata.com/resource/pubmed/id/15000555
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
2004-3-5
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pubmed:abstractText |
Local infection control measures, antibiotic consumption and patient demographics from 1999-2000 together with bacteriological analyses were investigated in 29 ICUs participating in the ICU-STRAMA programme. The median antibiotic consumption per ICU was 1147 (range 605-2143) daily doses per 1000 occupied bed d (DDD1000). Antibiotics to which > 90% of isolates of an organism were susceptible were defined as treatment alternatives (TA90). The mean number of TA90 was low (1-2 per organism) for Enterococcus faecium (vancomycin:VAN), coagulase negative staphylococci (VAN), Pseudomonas aeruginosa (ceftazidime:CTZ, netilmicin: NET) and Stenotrophomonas maltophilia (CTZ, trimethoprim-sulfamethoxazole: TSU), but higher (3-7) for Acinetobacter spp. (imipenem:IMI, NET, TSU), Enterococcus faecalis (ampicillin:AMP, IMI, VAN), Serratia spp. (ciprofloxacin:CIP, IMI, NET), Enterobacter spp. (CIP, IMI, NET, TSU), E. coli (cefuroxime:CXM, cefotaxime/eftazidime:CTX/CTZ, CIP, IMI, NET, piperacillin-tazobactam:PTZ, TSU), Klebsiella spp. (CTX/CTZ CIP, IMI, NET, PTZ, TSU) and Staphylococcus aureus (clindamycin, fusidic acid, NET, oxacillin, rifampicin, VAN). Of S. aureus isolates 2% were MRSA. Facilities for alcohol hand disinfection at each bed were available in 96% of the ICUs. The numbers of TA90 available were apparently higher than in ICUs in southern Europe and the US, despite a relatively high antibiotic consumption. This may be due to a moderate ecological impact of the used agents and the infection control routines in Swedish ICUs.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0036-5548
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pubmed:author |
pubmed-author:BurmanLars GLG,
pubmed-author:CarsOttoO,
pubmed-author:ErlandssonMarcusM,
pubmed-author:GillHansH,
pubmed-author:HanbergerHåkanH,
pubmed-author:ICU-STRAMA Study Group,
pubmed-author:LindgrenSuneS,
pubmed-author:NilssonLennart ELE,
pubmed-author:Olsson-LiljequistBarbroB,
pubmed-author:WaltherStenS
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pubmed:issnType |
Print
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pubmed:volume |
36
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
24-30
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:15000555-Adult,
pubmed-meshheading:15000555-Anti-Bacterial Agents,
pubmed-meshheading:15000555-Cohort Studies,
pubmed-meshheading:15000555-Cross Infection,
pubmed-meshheading:15000555-Drug Resistance, Bacterial,
pubmed-meshheading:15000555-Drug Resistance, Multiple, Bacterial,
pubmed-meshheading:15000555-Female,
pubmed-meshheading:15000555-Gram-Negative Bacteria,
pubmed-meshheading:15000555-Gram-Positive Bacteria,
pubmed-meshheading:15000555-Humans,
pubmed-meshheading:15000555-Incidence,
pubmed-meshheading:15000555-Intensive Care Units,
pubmed-meshheading:15000555-Male,
pubmed-meshheading:15000555-Microbial Sensitivity Tests,
pubmed-meshheading:15000555-Middle Aged,
pubmed-meshheading:15000555-Probability,
pubmed-meshheading:15000555-Questionnaires,
pubmed-meshheading:15000555-Retrospective Studies,
pubmed-meshheading:15000555-Risk Factors,
pubmed-meshheading:15000555-Sweden
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pubmed:year |
2004
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pubmed:articleTitle |
High antibiotic susceptibility among bacterial pathogens in Swedish ICUs. Report from a nation-wide surveillance program using TA90 as a novel index of susceptibility.
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pubmed:affiliation |
Division of Infectious Diseases, Department of Molecular and Clinical Medicine, Faculty of Health Sciences, Linkoping, Sweden. Hakan.Hanberger@imk.liu.se
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
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