Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
2004-3-5
pubmed:abstractText
Local infection control measures, antibiotic consumption and patient demographics from 1999-2000 together with bacteriological analyses were investigated in 29 ICUs participating in the ICU-STRAMA programme. The median antibiotic consumption per ICU was 1147 (range 605-2143) daily doses per 1000 occupied bed d (DDD1000). Antibiotics to which > 90% of isolates of an organism were susceptible were defined as treatment alternatives (TA90). The mean number of TA90 was low (1-2 per organism) for Enterococcus faecium (vancomycin:VAN), coagulase negative staphylococci (VAN), Pseudomonas aeruginosa (ceftazidime:CTZ, netilmicin: NET) and Stenotrophomonas maltophilia (CTZ, trimethoprim-sulfamethoxazole: TSU), but higher (3-7) for Acinetobacter spp. (imipenem:IMI, NET, TSU), Enterococcus faecalis (ampicillin:AMP, IMI, VAN), Serratia spp. (ciprofloxacin:CIP, IMI, NET), Enterobacter spp. (CIP, IMI, NET, TSU), E. coli (cefuroxime:CXM, cefotaxime/eftazidime:CTX/CTZ, CIP, IMI, NET, piperacillin-tazobactam:PTZ, TSU), Klebsiella spp. (CTX/CTZ CIP, IMI, NET, PTZ, TSU) and Staphylococcus aureus (clindamycin, fusidic acid, NET, oxacillin, rifampicin, VAN). Of S. aureus isolates 2% were MRSA. Facilities for alcohol hand disinfection at each bed were available in 96% of the ICUs. The numbers of TA90 available were apparently higher than in ICUs in southern Europe and the US, despite a relatively high antibiotic consumption. This may be due to a moderate ecological impact of the used agents and the infection control routines in Swedish ICUs.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0036-5548
pubmed:author
pubmed:issnType
Print
pubmed:volume
36
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
24-30
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed-meshheading:15000555-Adult, pubmed-meshheading:15000555-Anti-Bacterial Agents, pubmed-meshheading:15000555-Cohort Studies, pubmed-meshheading:15000555-Cross Infection, pubmed-meshheading:15000555-Drug Resistance, Bacterial, pubmed-meshheading:15000555-Drug Resistance, Multiple, Bacterial, pubmed-meshheading:15000555-Female, pubmed-meshheading:15000555-Gram-Negative Bacteria, pubmed-meshheading:15000555-Gram-Positive Bacteria, pubmed-meshheading:15000555-Humans, pubmed-meshheading:15000555-Incidence, pubmed-meshheading:15000555-Intensive Care Units, pubmed-meshheading:15000555-Male, pubmed-meshheading:15000555-Microbial Sensitivity Tests, pubmed-meshheading:15000555-Middle Aged, pubmed-meshheading:15000555-Probability, pubmed-meshheading:15000555-Questionnaires, pubmed-meshheading:15000555-Retrospective Studies, pubmed-meshheading:15000555-Risk Factors, pubmed-meshheading:15000555-Sweden
pubmed:year
2004
pubmed:articleTitle
High antibiotic susceptibility among bacterial pathogens in Swedish ICUs. Report from a nation-wide surveillance program using TA90 as a novel index of susceptibility.
pubmed:affiliation
Division of Infectious Diseases, Department of Molecular and Clinical Medicine, Faculty of Health Sciences, Linkoping, Sweden. Hakan.Hanberger@imk.liu.se
pubmed:publicationType
Journal Article, Comparative Study, Research Support, Non-U.S. Gov't