rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
2004-3-4
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pubmed:abstractText |
It has been hypothesized that sleep deprivation represents an oxidative challenge for the brain and that sleep may have a protective role against oxidative damage. This study was designed to test this hypothesis by measuring in rats the effects of sleep loss on markers of oxidative stress (oxidant production and antioxidant enzyme activities) as well as on markers of cellular oxidative damage (lipid peroxidation and protein oxidation).
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0161-8105
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
1
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pubmed:volume |
27
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
27-35
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pubmed:dateRevised |
2009-1-29
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pubmed:meshHeading |
pubmed-meshheading:14998234-Animals,
pubmed-meshheading:14998234-Biological Markers,
pubmed-meshheading:14998234-Brain,
pubmed-meshheading:14998234-Electroencephalography,
pubmed-meshheading:14998234-Electromyography,
pubmed-meshheading:14998234-Enzyme Inhibitors,
pubmed-meshheading:14998234-Lipid Peroxidation,
pubmed-meshheading:14998234-Male,
pubmed-meshheading:14998234-Oxidants,
pubmed-meshheading:14998234-Oxidative Stress,
pubmed-meshheading:14998234-Rats,
pubmed-meshheading:14998234-Rats, Wistar,
pubmed-meshheading:14998234-Sleep, REM,
pubmed-meshheading:14998234-Sleep Deprivation,
pubmed-meshheading:14998234-Sodium Azide,
pubmed-meshheading:14998234-Spectrometry, Fluorescence,
pubmed-meshheading:14998234-Superoxide Dismutase,
pubmed-meshheading:14998234-Wakefulness
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pubmed:year |
2004
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pubmed:articleTitle |
Sleep deprivation and cellular responses to oxidative stress.
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pubmed:affiliation |
Department of Psychiatry, University of Wisconsin, Madison 53719, USA.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
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