Source:http://linkedlifedata.com/resource/pubmed/id/14997441
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
2004-3-3
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pubmed:abstractText |
The telomeres are the nucleoproteic structures present at the ends of eukaryotic chromosomes. One can compare them to the protective ends of a shoelace; when the ends get eroded, the shoelace disintegrates and we dispose of it. The same thus applies to the chromosomes; when telomeres reach a critical threshold for function, the genome becomes unstable and the cell senesces. Therefore, telomeres, and particularly their terminal DNA structures, are critical for the integrity of the genome.
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pubmed:language |
fre
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0767-0974
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
20
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
207-12
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pubmed:dateRevised |
2007-4-13
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pubmed:meshHeading | |
pubmed:year |
2004
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pubmed:articleTitle |
[The structures at the termini of chromosomes: what is there hidden under the cap ?].
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pubmed:affiliation |
Département de microbiologie et d'infectiologie, Faculté de médecine, Université de Sherbrooke, 3001, 12e Avenue Nord, Sherbrooke, Québec, J1H 5N4, Canada.
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pubmed:publicationType |
Journal Article,
English Abstract,
Review,
Research Support, Non-U.S. Gov't
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