Linked Life Data

14993360

Source:http://linkedlifedata.com/resource/pubmed/id/14993360

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
2004-3-2
pubmed:abstractText
Although cytokines are critical in maintaining normal physiology, excessive production of these proteins can lead to pathological consequences. Inhibitors of cytokine production or action are therefore widely investigated as potential therapeutic agents in a variety of immune and inflammatory diseases. Indeed, the successful application of inhibitors of tumor necrosis factor-alpha in rheumatoid arthritis and Crohn's disease heralds the great therapeutic potential of biopharmaceutical agents to counteract cytokine activities. Emerging opportunities for new therapeutics, as well as the challenges we face in their use and development, are described in this review.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
1543-2548
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
2
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
36-46
pubmed:dateRevised
2009-6-22
pubmed:meshHeading
pubmed:year
2002
pubmed:articleTitle
Coming of age: anti-cytokine therapies.
pubmed:affiliation
Research & Development Centocor, Inc. 200 Great Valley Parkway, Malvern, PA 19355, USA. songx@centocor.com
pubmed:publicationType
Journal Article, Review