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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3
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pubmed:dateCreated |
2004-3-2
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pubmed:abstractText |
The broader autism phenotype includes relatives of individuals with autism who display social and language deficits that are qualitatively similar to those of autism but less severe. In previous studies of monozygotic twins discordant for autism, more than 75% of the twins without autism displayed the broader phenotype. Differences in neuroanatomy between discordant monozygotic twins might be associated with the narrow and broader behavioral phenotypes. The authors examined the relationship of twin pair differences in clinical phenotype to differences in neuroanatomic phenotype.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
0002-953X
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
161
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
539-46
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:14992981-Adolescent,
pubmed-meshheading:14992981-Autistic Disorder,
pubmed-meshheading:14992981-Brain,
pubmed-meshheading:14992981-Cerebellum,
pubmed-meshheading:14992981-Cerebral Cortex,
pubmed-meshheading:14992981-Cerebral Ventricles,
pubmed-meshheading:14992981-Child,
pubmed-meshheading:14992981-Child, Preschool,
pubmed-meshheading:14992981-Diseases in Twins,
pubmed-meshheading:14992981-Dominance, Cerebral,
pubmed-meshheading:14992981-Female,
pubmed-meshheading:14992981-Humans,
pubmed-meshheading:14992981-Image Processing, Computer-Assisted,
pubmed-meshheading:14992981-Infant, Newborn,
pubmed-meshheading:14992981-Magnetic Resonance Imaging,
pubmed-meshheading:14992981-Male,
pubmed-meshheading:14992981-Phenotype,
pubmed-meshheading:14992981-Reference Values,
pubmed-meshheading:14992981-Twins, Monozygotic
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pubmed:year |
2004
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pubmed:articleTitle |
Neuroanatomic variation in monozygotic twin pairs discordant for the narrow phenotype for autism.
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pubmed:affiliation |
Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD, USA. katesw@upstate.edu
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't,
Twin Study
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