Source:http://linkedlifedata.com/resource/pubmed/id/14988105
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
12
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pubmed:dateCreated |
2004-8-12
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pubmed:abstractText |
Phylogenetic shadowing is a comparative genomics principle that allows for the discovery of conserved regions in sequences from multiple closely related organisms. We develop a formal probabilistic framework for combining phylogenetic shadowing with feature-based functional annotation methods. The resulting model, a generalized hidden Markov phylogeny (GHMP), applies to a variety of situations where functional regions are to be inferred from evolutionary constraints.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
1367-4803
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
12
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pubmed:volume |
20
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1850-60
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:14988105-Algorithms,
pubmed-meshheading:14988105-Chromosome Mapping,
pubmed-meshheading:14988105-Evolution, Molecular,
pubmed-meshheading:14988105-Gene Expression Profiling,
pubmed-meshheading:14988105-Markov Chains,
pubmed-meshheading:14988105-Models, Genetic,
pubmed-meshheading:14988105-Models, Statistical,
pubmed-meshheading:14988105-Phylogeny,
pubmed-meshheading:14988105-Sequence Alignment,
pubmed-meshheading:14988105-Sequence Analysis, DNA,
pubmed-meshheading:14988105-Sequence Homology, Nucleic Acid,
pubmed-meshheading:14988105-Software
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pubmed:year |
2004
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pubmed:articleTitle |
Multiple-sequence functional annotation and the generalized hidden Markov phylogeny.
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pubmed:affiliation |
Department of Statistics, University of California, 367 Evans Hall, Berkeley, CA 94720, USA.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, U.S. Gov't, Non-P.H.S.,
Evaluation Studies
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