Source:http://linkedlifedata.com/resource/pubmed/id/14987069
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
2004-2-27
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pubmed:abstractText |
This review article will emphasize recent research in the Natural Products Laboratory, School of Pharmacy, University of North Carolina at Chapel Hill, on various classes of plant-derived compounds that possess potent antitumor or anti-HIV activity. These compounds were obtained by bioactivity- and mechanism of action-directed isolation and characterization coupled with rational drug design-based modification and analogue synthesis. Structural modification, SAR, and mechanism of action studies are discussed.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0163-3864
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
67
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
273-83
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:14987069-Anti-HIV Agents,
pubmed-meshheading:14987069-Antineoplastic Agents,
pubmed-meshheading:14987069-Biological Factors,
pubmed-meshheading:14987069-Drug Design,
pubmed-meshheading:14987069-Molecular Structure,
pubmed-meshheading:14987069-Plants, Medicinal,
pubmed-meshheading:14987069-Structure-Activity Relationship
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pubmed:year |
2004
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pubmed:articleTitle |
Current developments in the discovery and design of new drug candidates from plant natural product leads.
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pubmed:affiliation |
Natural Products Laboratory, School of Pharmacy, University of North Carolina, Chapel Hill, North Carolina 27599-7360, USA. khlee@unc.edu
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Review,
Research Support, Non-U.S. Gov't
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