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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
6C
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pubmed:dateCreated |
2004-2-25
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pubmed:abstractText |
Multidrug resistance (MDR) is a major reason for the poor outcome of advanced pediatric liver malignancies. The P-glycoprotein (P-gP), which contributes to this phenomenon, has been potently antagonized in other tumors. Our aim was to investigate the influence of P-gP antagonizers on the chemotherapy of pediatric liver malignancies in vitro.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
0250-7005
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
23
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
4607-11
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:14981903-Acridines,
pubmed-meshheading:14981903-Antineoplastic Agents,
pubmed-meshheading:14981903-Carcinoma, Hepatocellular,
pubmed-meshheading:14981903-Cell Survival,
pubmed-meshheading:14981903-Child,
pubmed-meshheading:14981903-Cisplatin,
pubmed-meshheading:14981903-Cyclosporins,
pubmed-meshheading:14981903-Doxorubicin,
pubmed-meshheading:14981903-Drug Resistance, Multiple,
pubmed-meshheading:14981903-Hepatoblastoma,
pubmed-meshheading:14981903-Humans,
pubmed-meshheading:14981903-Liver Neoplasms,
pubmed-meshheading:14981903-P-Glycoprotein,
pubmed-meshheading:14981903-Tetrahydroisoquinolines,
pubmed-meshheading:14981903-Tumor Cells, Cultured
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pubmed:articleTitle |
P-glycoprotein modulation improves in vitro chemosensitivity in malignant pediatric liver tumors.
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pubmed:affiliation |
Department of Pediatric Surgery, University of Tübingen, Hoppe-Seyler-Str. 3, 72076 Tübingen, Germany. Steven.Warmann@med.uni-tuebingen.de
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pubmed:publicationType |
Journal Article
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