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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
4
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pubmed:dateCreated |
2004-2-23
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pubmed:abstractText |
Carbonic anhydrase 9 (CA9) is the most promising molecular marker described for renal cell carcinoma (RCC) to date. We investigated whether transduction of monocytes from peripheral blood with adenovirus encoding the CA9 gene (AdV-CA9) could stimulate a T-cell mediated immune response against cancer cells expressing CA9. The ability to consistently generate a T-cell response is an important step toward the development of a CA9-specific RCC vaccine.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
1078-0432
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
15
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pubmed:volume |
10
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1421-9
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pubmed:dateRevised |
2006-4-21
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pubmed:meshHeading |
pubmed-meshheading:14977845-Adenoviridae,
pubmed-meshheading:14977845-Blotting, Western,
pubmed-meshheading:14977845-Cancer Vaccines,
pubmed-meshheading:14977845-Carbonic Anhydrases,
pubmed-meshheading:14977845-Carcinoma, Renal Cell,
pubmed-meshheading:14977845-Cell Adhesion,
pubmed-meshheading:14977845-Cell Line, Tumor,
pubmed-meshheading:14977845-Cloning, Molecular,
pubmed-meshheading:14977845-Cytokines,
pubmed-meshheading:14977845-Flow Cytometry,
pubmed-meshheading:14977845-Genetic Vectors,
pubmed-meshheading:14977845-Humans,
pubmed-meshheading:14977845-Immunotherapy,
pubmed-meshheading:14977845-Kidney Neoplasms,
pubmed-meshheading:14977845-Leukocytes, Mononuclear,
pubmed-meshheading:14977845-Microscopy, Phase-Contrast,
pubmed-meshheading:14977845-Monocytes,
pubmed-meshheading:14977845-Phenotype,
pubmed-meshheading:14977845-T-Lymphocytes
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pubmed:year |
2004
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pubmed:articleTitle |
Generation of kidney cancer-specific antitumor immune responses using peripheral blood monocytes transduced with a recombinant adenovirus encoding carbonic anhydrase 9.
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pubmed:affiliation |
Departments of Urology and Medicine, University of California Los Angeles, Los Angeles, California 90095-1738, USA.
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pubmed:publicationType |
Journal Article
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