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rdf:type |
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lifeskim:mentions |
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pubmed:dateCreated |
2004-2-20
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pubmed:abstractText |
We describe a method for mapping quantitative trait loci that allows for locus heterogeneity. A genome-wide linkage analysis of blood pressure was performed using sib-pair data from the Framingham Heart Study. Evidence of linkage was found on four markers (GATA89G08, GATA23D06, GATA14E09, and 049xd2) at a significance level of 0.01. Two of them (GATA14E09 and 049xd2) seem to overlap with linkage signals reported previously, while the other two are not linked to any known signals.
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pubmed:grant |
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/14975146-10067786,
http://linkedlifedata.com/resource/pubmed/commentcorrection/14975146-10597525,
http://linkedlifedata.com/resource/pubmed/commentcorrection/14975146-10878659,
http://linkedlifedata.com/resource/pubmed/commentcorrection/14975146-11034945,
http://linkedlifedata.com/resource/pubmed/commentcorrection/14975146-11287741,
http://linkedlifedata.com/resource/pubmed/commentcorrection/14975146-11791211,
http://linkedlifedata.com/resource/pubmed/commentcorrection/14975146-11793769,
http://linkedlifedata.com/resource/pubmed/commentcorrection/14975146-11875187,
http://linkedlifedata.com/resource/pubmed/commentcorrection/14975146-12566738,
http://linkedlifedata.com/resource/pubmed/commentcorrection/14975146-12574080,
http://linkedlifedata.com/resource/pubmed/commentcorrection/14975146-14081488,
http://linkedlifedata.com/resource/pubmed/commentcorrection/14975146-4157472,
http://linkedlifedata.com/resource/pubmed/commentcorrection/14975146-9758634
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
1471-2156
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
4 Suppl 1
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
S78
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pubmed:dateRevised |
2010-11-18
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pubmed:meshHeading |
pubmed-meshheading:14975146-Adult Children,
pubmed-meshheading:14975146-Blood Pressure,
pubmed-meshheading:14975146-Chromosomes, Human, Pair 16,
pubmed-meshheading:14975146-Chromosomes, Human, Pair 5,
pubmed-meshheading:14975146-Chromosomes, Human, Pair 8,
pubmed-meshheading:14975146-Cohort Studies,
pubmed-meshheading:14975146-Female,
pubmed-meshheading:14975146-Genetic Heterogeneity,
pubmed-meshheading:14975146-Genetic Linkage,
pubmed-meshheading:14975146-Genetic Markers,
pubmed-meshheading:14975146-Genome, Human,
pubmed-meshheading:14975146-Humans,
pubmed-meshheading:14975146-Likelihood Functions,
pubmed-meshheading:14975146-Longitudinal Studies,
pubmed-meshheading:14975146-Male,
pubmed-meshheading:14975146-Matched-Pair Analysis,
pubmed-meshheading:14975146-Models, Genetic,
pubmed-meshheading:14975146-Quantitative Trait Loci,
pubmed-meshheading:14975146-Siblings
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pubmed:year |
2003
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pubmed:articleTitle |
Genome-wide linkage analysis of blood pressure under locus heterogeneity.
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pubmed:affiliation |
Department of Biostatistics, Division of Statistical Genetics, The University of Iowa, Iowa City, USA. xinqun-yang@uiowa.edu
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
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