Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
2004-2-20
pubmed:abstractText
We report the novel finding of matrix-rich "fibrin" cuffs in chronic nonspecific oral ulceration and propose a possible role for these lesions. Pericapillary cuffs are typically found in chronic venous ulceration. Vascular cuffs, which form in the base and margins of leg ulcers, have been reported to contain fibrin, laminin, fibronectin, tenascin, and types I and III collagen. Histologically identical vascular cuffs are present in oral ulcers of unusually prolonged chronicity and their occurrence in the oral cavity suggests that chronic venous insufficiency and back pressure are not essential to their formation. It is proposed that the matrix-rich pericapillary cuffs may act as a scaffold for angiogenesis in ulceration of prolonged duration.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
1067-1927
pubmed:author
pubmed:issnType
Print
pubmed:volume
12
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
18-23
pubmed:dateRevised
2006-11-7
pubmed:meshHeading
pubmed:articleTitle
Role of "fibrin" cuffs in chronic nonspecific oral ulceration.
pubmed:affiliation
University Dental Hospital of Manchester, Oral & Maxillofacial Sciences Group, Manchester, United Kingdom. Ameeta.Joshi@man.ac.uk
pubmed:publicationType
Journal Article