Linked Life Data

14972455

Source:http://linkedlifedata.com/resource/pubmed/id/14972455

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2-3
pubmed:dateCreated
2004-2-19
pubmed:abstractText
The 19th century debates on mammalian classification in the light of the new evolutionary thinking led to controversies between Thomas Huxley and Richard Owen concerning the value of the placenta as a representative key organ. As a main point in his argument, Huxley provided a detailed description of a sectioned rat placenta, highlighting the importance of decidualization of the uterus as an argument supporting an evolutionary relationship between rodents, insectivores and primates, an idea hotly contested by Owen. In addition, he illustrated and correctly interpreted the maternal blood supply from uterus to placenta in striking detail. During the succeeding decades the key role of trophoblast in placenta formation was discovered, and the decidua became neglected in later comparative studies. Nevertheless, at the present time trophoblast-decidual interaction is regarded as an extremely important feature of placental development in both primates and rodents, and Huxley can therefore rightfully be considered as an early pioneer in placental research.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:issn
0143-4004
pubmed:author
pubmed:issnType
Print
pubmed:volume
25
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
233-7
pubmed:dateRevised
2010-11-18
pubmed:meshHeading
pubmed:articleTitle
Thomas Huxley and the rat placenta in the early debates on evolution.
pubmed:affiliation
Department of Obstetrics and Gynaecology, Universitair Ziekenhuis Gasthuisberg, Katholieke Universiteit Leuven,Leuven B3000, Belgium. robert.pijnenborg@uz.kuleuven.ac.be
pubmed:publicationType
Journal Article, Biography, Review, Historical Article