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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
2004-2-17
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pubmed:abstractText |
Vasopeptidase inhibitors (VPi) may provide a new means of treating hypertension and congestive heart failure, because they simultaneously block angiotensin-converting enzyme (ACE) and neutral endopeptidase-24.11 (NEP-24.11), thereby inhibiting the renin-angiotensin system and enhancing vasodilator and natriuretic substances such as kinins and natriuretic peptides.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Angiotensin-Converting Enzyme...,
http://linkedlifedata.com/resource/pubmed/chemical/Antihypertensive Agents,
http://linkedlifedata.com/resource/pubmed/chemical/Collagen,
http://linkedlifedata.com/resource/pubmed/chemical/Indans,
http://linkedlifedata.com/resource/pubmed/chemical/Neprilysin,
http://linkedlifedata.com/resource/pubmed/chemical/Propionates,
http://linkedlifedata.com/resource/pubmed/chemical/Pyridines,
http://linkedlifedata.com/resource/pubmed/chemical/Ramipril,
http://linkedlifedata.com/resource/pubmed/chemical/Thiazepines,
http://linkedlifedata.com/resource/pubmed/chemical/candoxatril,
http://linkedlifedata.com/resource/pubmed/chemical/omapatrilat
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
1071-9164
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
10
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
83-9
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:14966779-Angiotensin-Converting Enzyme Inhibitors,
pubmed-meshheading:14966779-Animals,
pubmed-meshheading:14966779-Antihypertensive Agents,
pubmed-meshheading:14966779-Collagen,
pubmed-meshheading:14966779-Disease Models, Animal,
pubmed-meshheading:14966779-Echocardiography,
pubmed-meshheading:14966779-Heart,
pubmed-meshheading:14966779-Heart Failure,
pubmed-meshheading:14966779-Indans,
pubmed-meshheading:14966779-Liver,
pubmed-meshheading:14966779-Lung,
pubmed-meshheading:14966779-Mice,
pubmed-meshheading:14966779-Mice, Knockout,
pubmed-meshheading:14966779-Muscle Cells,
pubmed-meshheading:14966779-Neprilysin,
pubmed-meshheading:14966779-Organ Size,
pubmed-meshheading:14966779-Propionates,
pubmed-meshheading:14966779-Pyridines,
pubmed-meshheading:14966779-Ramipril,
pubmed-meshheading:14966779-Thiazepines,
pubmed-meshheading:14966779-Treatment Outcome,
pubmed-meshheading:14966779-Ventricular Function, Left,
pubmed-meshheading:14966779-Ventricular Remodeling
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pubmed:year |
2004
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pubmed:articleTitle |
Dual inhibition of ACE and NEP provides greater cardioprotection in mice with heart failure.
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pubmed:affiliation |
Hypertension and Vascular Research Division, Henry Ford Hospital, 2799 West Grand Boulevard, Detroit, MI 48202-2689, USA.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
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