|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
3
|
|
pubmed:dateCreated |
2004-2-25
|
|
pubmed:abstractText |
The degree of penetration of an antibiotic into the infected site is an important determinant of therapeutic success. Levofloxacin is widely used in the treatment of serious infections. However, there are only few studies concerning its diffusion into bone tissue and none concerning its diffusion into synovial tissue. Our objective was to quantify levofloxacin bone and synovial tissue penetration and to compare our data with the breakpoint for susceptible organisms.
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pubmed:language |
eng
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|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Mar
|
|
pubmed:issn |
0305-7453
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
53
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
533-5
|
|
pubmed:dateRevised |
2006-11-15
|
|
pubmed:meshHeading |
pubmed-meshheading:14963066-Aged,
pubmed-meshheading:14963066-Anti-Infective Agents,
pubmed-meshheading:14963066-Arthroplasty, Replacement, Hip,
pubmed-meshheading:14963066-Bacteria,
pubmed-meshheading:14963066-Bone and Bones,
pubmed-meshheading:14963066-Chromatography, High Pressure Liquid,
pubmed-meshheading:14963066-Female,
pubmed-meshheading:14963066-Humans,
pubmed-meshheading:14963066-Injections, Intravenous,
pubmed-meshheading:14963066-Male,
pubmed-meshheading:14963066-Microbial Sensitivity Tests,
pubmed-meshheading:14963066-Ofloxacin,
pubmed-meshheading:14963066-Synovial Membrane
|
|
pubmed:year |
2004
|
|
pubmed:articleTitle |
Diffusion of levofloxacin into bone and synovial tissues.
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|
pubmed:affiliation |
Department of Anaesthesiology and Intensive Care, Hôtel-Dieu Hospital, Lyon, France.
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|
pubmed:publicationType |
Journal Article,
Clinical Trial,
Research Support, Non-U.S. Gov't
|
