Linked Life Data

14961048

Source:http://linkedlifedata.com/resource/pubmed/id/14961048

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
2004-7-23
pubmed:abstractText
Erectile dysfunction (ED) is commonly associated with depressed mood and diminished quality of life (QoL), but few studies have investigated the causal associations involved. Therefore, we evaluated the correlation between several measures of mood, QoL, and sexual function in a retrospective analysis of a sample of depressed men (n=152), with ED enrolled in a clinical trial of sildenafil citrate (VIAGRA). Strong correlations were observed at baseline among measures of erectile function (EF), mood, and overall QoL. Significant treatment effects were observed on all three domains, with significant interactions between changes in mood and QoL. Based on multiple regression and path analysis, a model was developed in which EF changes were associated with improved mood and quality of sexual life, which resulted in improved partner satisfaction, family life, and overall life satisfaction. These data suggest that QoL changes associated with ED therapy may be mediated by changes in sexual function, mood, and family relationships.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
0955-9930
pubmed:author
pubmed:issnType
Print
pubmed:volume
16
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
334-40
pubmed:dateRevised
2007-11-15
pubmed:meshHeading
pubmed-meshheading:14961048-Adolescent, pubmed-meshheading:14961048-Adult, pubmed-meshheading:14961048-Affect, pubmed-meshheading:14961048-Depressive Disorder, pubmed-meshheading:14961048-Double-Blind Method, pubmed-meshheading:14961048-Erectile Dysfunction, pubmed-meshheading:14961048-Humans, pubmed-meshheading:14961048-Male, pubmed-meshheading:14961048-Models, Psychological, pubmed-meshheading:14961048-Phosphodiesterase Inhibitors, pubmed-meshheading:14961048-Piperazines, pubmed-meshheading:14961048-Psychiatric Status Rating Scales, pubmed-meshheading:14961048-Purines, pubmed-meshheading:14961048-Quality of Life, pubmed-meshheading:14961048-Regression Analysis, pubmed-meshheading:14961048-Sexual Behavior, pubmed-meshheading:14961048-Sulfones, pubmed-meshheading:14961048-Treatment Outcome
pubmed:year
2004
pubmed:articleTitle
Quality of life, mood, and sexual function: a path analytic model of treatment effects in men with erectile dysfunction and depressive symptoms.
pubmed:affiliation
University of Medicine and Dentistry, Robert Wood Johnson Medical School, Piscataway, New Jersey 08554-5653, USA. rosen@umdnj.edu
pubmed:publicationType
Journal Article, Clinical Trial, Randomized Controlled Trial, Multicenter Study