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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
11A
|
pubmed:dateCreated |
1993-3-2
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pubmed:abstractText |
This double-blind study of dihydroergocristine (DHEC, CAS 17479-19-5) versus placebo was performed in 240 elderly patients affected by chronic cerebrovascular disease or organic brain syndrome. The therapy was carried on for one year. Results pointed out a decrease of SCAG total score and a significant improvement of the target items "confusion, mental alertness and memory performance" after DHEC versus placebo. Furthermore the data show that DHEC maintained its activity throughout the 12-month trial period. Very few and mild side-effects were reported for both groups, thus confirming the well known good safety of the compound. Based on results of this 1-year investigation, it is concluded that DHEC treatment should not be abruptly interrupted, but continued for as long as possible.
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pubmed:language |
ger
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pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Nov
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pubmed:issn |
0004-4172
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
42
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pubmed:owner |
NLM
|
pubmed:authorsComplete |
N
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pubmed:pagination |
1414-6
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:1492865-Aged,
pubmed-meshheading:1492865-Cognition Disorders,
pubmed-meshheading:1492865-Dihydroergotoxine,
pubmed-meshheading:1492865-Female,
pubmed-meshheading:1492865-Humans,
pubmed-meshheading:1492865-Male,
pubmed-meshheading:1492865-Memory Disorders,
pubmed-meshheading:1492865-Middle Aged
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pubmed:year |
1992
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pubmed:articleTitle |
[One-year therapy with dihydroergocristine for treatment of impaired alertness and memory in elderly patients. Placebo-controlled multicenter study].
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pubmed:affiliation |
Abteilung für Innere Medizin, Krankenhaus von Vaprio, d'Adda, Mailand, Italien.
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pubmed:publicationType |
Journal Article,
Clinical Trial,
English Abstract,
Randomized Controlled Trial,
Multicenter Study
|