Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
1993-2-25
pubmed:abstractText
Spirometry and impedance of the respiratory system were compared after increasing rates of isocapnic cold air hyperventilation (IHCA) in 10 asthmatics and 11 healthy nonsmokers. In the control group IHCA at 60% of indirect maximum breathing capacity (IMBC) resulted in a significant, equal increase in resistance at lower and higher frequencies, suggesting central airway constriction. In the asthmatics negative frequency dependence of resistance and a significant increase in resonant frequency and decrease in the reactance at 8 Hz were found at 40 and 60% IMBC. These changes suggest an increase in the resistance of the peripheral airways. The frequency dependence of resistance and resonant frequency were found to be the most sensitive measures to differentiate between normals and asthmatics. It is concluded that impedance measurements provide a suited method to assess the response in cold air provocation tests.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:issn
0025-7931
pubmed:author
pubmed:issnType
Print
pubmed:volume
59
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
259-64
pubmed:dateRevised
2009-11-11
pubmed:meshHeading
pubmed:year
1992
pubmed:articleTitle
Respiratory impedance measurements in a dose-response study of isocapnic hyperventilation with cold air.
pubmed:affiliation
Department of Pulmonary Diseases, University Hospital Maastricht, University of Limburg, The Netherlands.
pubmed:publicationType
Journal Article