Linked Life Data

1487849

Source:http://linkedlifedata.com/resource/pubmed/id/1487849

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1993-2-22
pubmed:abstractText
Regional cerebral blood flow (rCBF) during the resting state was measured using the 133Xe inhalation technique in 39 patients diagnosed as having schizophrenic disorder according to the DSM-III criteria and 30 age- and sex-matched healthy volunteers. All the patients were receiving neuroleptic medication. The bilateral hemispheric mean flow values in the schizophrenic patients decreased significantly and the relative flow distribution reduced significantly only in the left frontal region compared to the controls. The lower the left frontal blood flow in schizophrenics, the more pronounced were the negative symptoms including blunted affect, avolition-apathy and inattention. These results suggest that the negative symptoms in schizophrenics are related to left frontal lobe dysfunction.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
0912-2036
pubmed:author
pubmed:issnType
Print
pubmed:volume
46
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
653-7
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1992
pubmed:articleTitle
Left hypofrontality correlates with blunted affect in schizophrenia.
pubmed:affiliation
Department of Neuropsychiatry, Toyama Medical and Pharmaceutical University, Japan.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't